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. 2020 Jun;25(22):2001010.
doi: 10.2807/1560-7917.ES.2020.25.22.2001010.

SARS-CoV-2-related paediatric inflammatory multisystem syndrome, an epidemiological study, France, 1 March to 17 May 2020

Alexandre Belot  1 , Denise Antona  2 , Sylvain Renolleau  3 , Etienne Javouhey  3 , Véronique Hentgen  4 , François Angoulvant  4 , Christophe Delacourt  5 , Xavier Iriart  6 , Caroline Ovaert  6 , Brigitte Bader-Meunier  7 , Isabelle Kone-Paut  7 , Daniel Levy-Bruhl  2
Affiliations

SARS-CoV-2-related paediatric inflammatory multisystem syndrome, an epidemiological study, France, 1 March to 17 May 2020

Alexandre Belot et al. Euro Surveill. 2020 Jun.

Abstract

End of April 2020, French clinicians observed an increase in cases presenting with paediatric inflammatory multisystem syndrome (PIMS). Nationwide surveillance was set up and demonstrated temporospatial association with the coronavirus disease (COVID-19) epidemic for 156 reported cases as at 17 May: 108 were classified as confirmed (n = 79), probable (n = 16) or possible (n = 13) post-COVID-19 PIMS cases. A continuum of clinical features from Kawasaki-like disease to myocarditis was observed, requiring intensive care in 67% of cases.

Keywords: COVID-19; Kawasaki disease; SARS-CoV2; children; inflammation; myocarditis; post-infectious disease.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Flowchart of paediatric inflammatory multisystem syndrome cases following classification, France, 1 March–17 May (n = 156)
Figure 2
Figure 2
Temporal distribution of COVID-19 hospitalisations and SARS-CoV2 hyperinflammatory paediatric cases, France, 2 March–17 May (n = 108)
Figure 3
Figure 3
Spatial distribution of COVID-19 hospitalisations and SARS-CoV-2 hyperinflammatory paediatric cases, France 1 March–17 May (n = 108)
Figure 4
Figure 4
Age distribution of paediatric inflammatory multisystem syndrome patients, France, 1 March–17 May (n = 108)
Figure 5
Figure 5
Venn diagram of clinical features of SARS-CoV-2-related paediatric inflammatory multisystem syndrome, France, 1 March–17 May (n = 108)
See this image and copyright information in PMC

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