Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep;81(3):452-482.
doi: 10.1016/j.jinf.2020.06.008. Epub 2020 Jun 8.

Interleukin-6 as prognosticator in patients with COVID-19

Elisa Grifoni  1 , Alice Valoriani  2 , Francesco Cei  2 , Roberta Lamanna  3 , Anna Maria Grazia Gelli  3 , Benedetta Ciambotti  3 , Vieri Vannucchi  4 , Federico Moroni  4 , Lorenzo Pelagatti  4 , Roberto Tarquini  2 , Giancarlo Landini  3 , Simone Vanni  5 , Luca Masotti  6
Affiliations
Comment

Interleukin-6 as prognosticator in patients with COVID-19

Elisa Grifoni et al. J Infect. 2020 Sep.
No abstract available

Keywords: COVID-19; Interleukin-6; Mortality; Prognosis; Respiratory failure.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Receiver operating characteristic (ROC) curve showing the predictive power of IL-6 for predicting progression to severe COVID-19 and/or in-hospital mortality.
See this image and copyright information in PMC

Comment in

Comment on

References

    1. Ye Q., Wang B., Mao J. The pathogenesis and treatment of the “Cytokine Storm” in COVID-19. J Infect. 2020;80:607–613. doi: 10.1016/j.jinf.2020.03.037. - DOI - PMC - PubMed
    1. Zhang Z.L., Hou Y.L., Li D.T., Li F.Z. Laboratory findings of COVID-19: a systematic review and meta-analysis [published online ahead of print, 2020 May 23] Scand J Clin Lab Investig. 2020:1‐7. doi: 10.1080/00365513.2020.1768587. - DOI - PMC - PubMed
    1. Herold T., Jurinovic V., Arnreich C. Elevated levels of interleukin-6 and CRP predict the need for mechanical ventilation in COVID-19 [published online ahead of print, 2020 May 18] J Allergy Clin Immunol. 2020 doi: 10.1016/j.jaci.2020.05.008. 10.1016/j.jaci.2020.05.008. - DOI - PMC - PubMed
    1. Aziz M., Fatima R., Assaly R. Elevated interleukin-6 and Severe COVID-19: a meta-analysis. J Med Virol. 2020 doi: 10.1002/jmv.25948. 10.1002/jmv.25948Online ahead of print. - DOI - PMC - PubMed
    1. Ji D., Zhang D., Xu J. Prediction for progression risk in patients with COVID-19 pneumonia: the CALL score. Clin Infect Dis. 2020 doi: 10.1093/cid/ciaa414. Online ahead of print. - DOI - PMC - PubMed