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Editorial
. 2020 Aug;79(8):991-993.
doi: 10.1136/annrheumdis-2020-218019. Epub 2020 Jun 11.

Smart battles: immunosuppression versus immunomodulation in the inflammatory RMDs

John D Isaacs  1 , Gerd R Burmester  2
Affiliations
Editorial

Smart battles: immunosuppression versus immunomodulation in the inflammatory RMDs

John D Isaacs et al. Ann Rheum Dis. 2020 Aug.
No abstract available

Keywords: biological therapy; cytokines; therapeutics.

PubMed Disclaimer

Conflict of interest statement

Competing interests: JDI: grant from Pfizer, fees for lectures and consulting: AbbVie, Amgen, Eli Lilly, Gilead, Merck & Co, Roche, UCB. GRB: honoraria for lectures and consulting: AbbVie, Amgen, BMS, Gilead, Janssen, Lilly, Novartis, Pfizer, Sanofi-Aventis, Roche, UCB.

References

    1. Baker KF, Isaacs JD. Novel therapies for immune-mediated inflammatory diseases: what can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn's disease and ulcerative colitis? Ann Rheum Dis 2018;77:175–87. 10.1136/annrheumdis-2017-211555 - DOI - PubMed
    1. Kang EH, Jin Y, Tong AY, et al. . Risk of serious infection among initiators of TNF inhibitors plus methotrexate versus triple therapy for rheumatoid arthritis: a cohort study. Arthritis Care Res 2019. 10.1002/acr.24038. [Epub ahead of print: 03 Aug 2019]. - DOI - PubMed
    1. Sepriano A, Kerschbaumer A, Smolen JS, et al. . Safety of synthetic and biological DMARDs: a systematic literature review Informing the 2019 update of the EULAR recommendations for the management of rheumatoid arthritis. Ann Rheum Dis 2020;79:760–70. 10.1136/annrheumdis-2019-216653 - DOI - PubMed
    1. Mercer LK, Regierer AC, Mariette X, et al. . Spectrum of lymphomas across different drug treatment groups in rheumatoid arthritis: a European registries collaborative project. Ann Rheum Dis 2017;76:2025–30. 10.1136/annrheumdis-2017-211623 - DOI - PMC - PubMed
    1. Ridker PM, Everett BM, Pradhan A, et al. . Low-Dose methotrexate for the prevention of atherosclerotic events. N Engl J Med 2019;380:752–62. 10.1056/NEJMoa1809798 - DOI - PMC - PubMed

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