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. 2020 Aug 27;383(9):885-886.
doi: 10.1056/NEJMc2013020. Epub 2020 Jun 12.

Natural History of Asymptomatic SARS-CoV-2 Infection

Aki Sakurai  1 , Toshiharu Sasaki  1 , Shigeo Kato  2 , Masamichi Hayashi  1 , Sei-Ichiro Tsuzuki  1 , Takuma Ishihara  3 , Mitsunaga Iwata  4 , Zenichi Morise  4 , Yohei Doi  4
Affiliations

Natural History of Asymptomatic SARS-CoV-2 Infection

Aki Sakurai et al. N Engl J Med. .
No abstract available

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Figures

Figure 1
Figure 1. Crossing-Point Values in RT-PCR Testing of Asymptomatic Persons with SARS-CoV-2 Infection.
Included in the analysis are persons who had at least one positive polymerase-chain-reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the hospital. With fluorescence-based real-time reverse-transcriptase PCR (RT-PCR), the number of cycles at which the fluorescence signal from amplification exceeds the background fluorescence level is determined as the crossing point (Cp), threshold cycle, or other measures by different instrument manufacturers. A lower value correlates with a higher copy number of the target nucleotide sequence.
See this image and copyright information in PMC

References

    1. Arons MM, Hatfield KM, Reddy SC, et al. Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med 2020;382:2081-2090. - PMC - PubMed
    1. Bai Y, Yao L, Wei T, et al. Presumed asymptomatic carrier transmission of COVID-19. JAMA 2020;323:1406-1407. - PMC - PubMed
    1. Kimball A, Hatfield KM, Arons M, et al. Asymptomatic and presymptomatic SARS-CoV-2 infections in residents of a long-term care skilled nursing facility — King County, Washington, March 2020. MMWR Morb Mortal Wkly Rep 2020;69:377-381. - PMC - PubMed
    1. Field briefing: Diamond Princess COVID-19 cases, 20 Feb update. Tokyo: National Institute of Infectious Diseases, February 21, 2020 (https://www.niid.go.jp/niid/en/2019-ncov-e/9417-covid-dp-fe-02.html).
    1. Ministry of Health, Labour and Welfare. Official report on the cruise ship Diamond Princess. March 5, 2020. (https://www.mhlw.go.jp/stf/newpage_09997.html).

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