Hypothesis to explain the severe form of COVID-19 in Northern Italy

Affiliations

¹ Public Health Department, Local Health Unit N. 2 "Marca Trevigiana", Treviso, Veneto Region, Italy l.cegolon@gmail.com.
² IRCCS Materno Infantile Burlo Garofolo, Trieste, Friuli-Venezia Giulia Region, Italy.
³ Children and Young People's Diabetes, University College London Hospitals NHS Foundation Trust, London, UK.
⁴ Cardiac, Thoracic and Vascular Sciences, Padua University Hospital, Padua, Veneto Region, Italy.
⁵ Public Health Department, Local Health Unit N. 2 "Marca Trevigiana", Treviso, Veneto Region, Italy.
⁶ Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Sardinia Region, Italy.
⁷ Partnership for Maternal, Newborn and Child Health, World Health Organization, Geneve, Switzerland.
⁸ Microbiology Department, Kingston Hospital NHS Foundation Trust, Kingston upon Thames, London, UK.

Luca Cegolon et al. BMJ Glob Health. 2020 Jun.

. 2020 Jun;5(6):e002564.

doi: 10.1136/bmjgh-2020-002564.

¹ Public Health Department, Local Health Unit N. 2 "Marca Trevigiana", Treviso, Veneto Region, Italy l.cegolon@gmail.com.
² IRCCS Materno Infantile Burlo Garofolo, Trieste, Friuli-Venezia Giulia Region, Italy.
³ Children and Young People's Diabetes, University College London Hospitals NHS Foundation Trust, London, UK.
⁴ Cardiac, Thoracic and Vascular Sciences, Padua University Hospital, Padua, Veneto Region, Italy.
⁵ Public Health Department, Local Health Unit N. 2 "Marca Trevigiana", Treviso, Veneto Region, Italy.
⁶ Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Sardinia Region, Italy.
⁷ Partnership for Maternal, Newborn and Child Health, World Health Organization, Geneve, Switzerland.
⁸ Microbiology Department, Kingston Hospital NHS Foundation Trust, Kingston upon Thames, London, UK.

No abstract available

Keywords: SARS; dengue; epidemiology; prevention strategies; public health.

Conflict of interest statement

Competing interests: None declared.

1. Worldometers Coronavirus COVID-19 outbreak, 2020. Available: https://www.worldometers.info/coronavirus/ [Accessed 17 Apr 2020].
1. World Health Organization Report of the WHO-China joint mission on coronavirus disease 2019 (COVID-19), 2020. Available: https://www.who.int/publications-detail/report-of-the-who-china-joint-mi... [Accessed 17 Apr 2020].
1. Chan JF-W, Yuan S, Kok K-H, et al. . A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020;395:514–23. 10.1016/S0140-6736(20)30154-9 - DOI - PMC - PubMed
1. Cao X. COVID-19: immunopathology and its implications for therapy. Nat Rev Immunol 2020;20:269–70. 10.1038/s41577-020-0308-3 - DOI - PMC - PubMed
1. Verity R, Okell LC, Dorigatti I, et al. . Estimates of the severity of coronavirus disease 2019: a model-based analysis. Lancet Infect Dis 2020;3099:30243–7. 10.1016/S1473-3099(20)30243-7 - DOI - PMC - PubMed