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Case Reports
. 2020 Nov;267(11):3121-3127.
doi: 10.1007/s00415-020-09986-y. Epub 2020 Jun 12.

Mixed central and peripheral nervous system disorders in severe SARS-CoV-2 infection

Affiliations
Case Reports

Mixed central and peripheral nervous system disorders in severe SARS-CoV-2 infection

H Chaumont et al. J Neurol. 2020 Nov.
No abstract available

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Conflict of interest statement

Dr. Chaumont reports having received travel grant from PEPS development, Roche and Pfizer. Dr. Roze reports served on scientific advisory boards for Orkyn, Aguettant, Merz-Pharma; received honoraria for speeches from Orkyn, Aguettant, Merz-Pharma, Medday-Pharma, Everpharma, International Parkinson and Movement disorders Society; received research support from Merz-Pharma, Orkyn, Aguettant, Elivie, Ipsen, Everpharma, Fondation Desmarest, AMADYS, Fonds de Dotation Brou de Laurière, Agence Nationale de la Recherche; received travel grant from Vitalair, PEPS development, Aguettant, Merz-Pharma, Ipsen, Merck, Orkyn, Elivie, Adelia Medical, Dystonia Medical Research Foundation, International Parkinson and Movement disorders Society, European Academy of Neurology, International Association of Parkinsonism and Related Disorders. Dr. Couratier reports having received travel grant from Allergan, Novartis, Esai, UCB, Medtronic, Merck Serono, Biogen, LFB, Teva, Icomed, GSK, Genzyme, Aguettant, Cyberonics and Merz-Pharma. Dr. Lannuzel reports having received research support from France Parkinson, PSP France, Agence Nationale de la Recherche, Fonds Européen de DEveloppement Regional, French Ministry of Health, University Hospital of Guadeloupe, received honoraria for a speech from Association des Neurologues du Québec; received travel grant from Vitalair, PEPS development, Merz-Pharma, International Parkinson and Movement disorders Society. Dr. San-Galli, Dr. Martino, Dr. Carles, and Dr. Joguet report no disclosures.

Figures

Fig. 1
Fig. 1
Timelines showing general and neurological symptoms onset, timing of hospital admission and discharge, timing of ICU admission and discharge, and paraclinical examinations and treatments. EEG, electroencephalogram; EMG electromyogram; ICU intensive care unit; IVIg intravenous immunoglobulin; MRI magnetic resonance imagery. P1: Patient 1 (M, 62 y.o), P2: Patient 2 (M, 72 y.o), P3: Patient 3 (M, 50 y.o), P4: Patient 4 (M, 66 y.o). For P2, cerebral and spinal MRI were performed at two different dates (days 49 and 62, respectively)

References

    1. Mao L, Jin H, Wang M, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan. China: JAMA Neurol; 2020. - PMC - PubMed
    1. Politi LS, Salsano E, Grimaldi M. Magnetic resonance imaging alteration of the brain in a patient with coronavirus disease 2019 (covid-19) and anosmia. JAMA Neurol. 2020 doi: 10.1001/jamaneurol.2020.2125. - DOI - PubMed
    1. Moriguchi T, Harii N, Goto J, et al. A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. Intern J Diseases. 2020;12:19–71. doi: 10.1016/j.ijid.2020.03.062. - DOI - PMC - PubMed
    1. Chaumont H, Etienne P, Roze E, et al. Acute meningoencephalitis in a patient with COVID-19. Revue Neurol. 2020;35(3):7–87. doi: 10.1016/j.neurol.2020.04.014. - DOI - PMC - PubMed
    1. Poyiadji N, Shahin G, Noujaim D, et al. COVID-19–associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features. Radiology. 2020;20:11–87. doi: 10.1148/radiol.2020201187. - DOI - PMC - PubMed