Equine Genotyping Arrays
- PMID: 32534852
- DOI: 10.1016/j.cveq.2020.03.001
Equine Genotyping Arrays
Abstract
High-quality genomic tools have been integral in understanding genomic architecture and function in the modern-day horse. The equine genetics community has a long tradition of pooling resources to develop genomic tools. Since the equine genome was sequenced in 2006, several iterations of high throughput genotyping arrays have been developed and released, enabling rapid and cost-effective genotyping. This review highlights the design considerations of each iteration, focusing on data available during development and outlining considerations in selecting the genetic variants included on each array. Additionally, we outline recent applications of equine genotyping arrays as well as future prospects and applications.
Keywords: Equine; GWAS; Genotyping array; Imputation; Population genomics; SNP.
Copyright © 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Disclosure This work was supported by USDA NIFA project 2012-67015-19432, Minnesota Agricultural Experiment Station Multi-state project MIN-62-090 and the National Animal Genome Project (NRSP8) through the equine genome coordinator: USDA-NRSP8 (2013-2018) horse-technical-committee coordinator funds. The funders had no role in the preparation of this manuscript.
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