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. 2020 Jun;17(3):15-16.
doi: 10.1111/1740-9713.01399. Epub 2020 May 27.

Tests in short supply? Try group testing

Christopher R Bilder  1 , Peter C Iwen  2 , Baha Abdalhamid  3 , Joshua M Tebbs  4 , Christopher S McMahan  5
Affiliations

Tests in short supply? Try group testing

Christopher R Bilder et al. Signif (Oxf). 2020 Jun.

Abstract

Christopher R. Bilder, Peter C. Iwen, Baha Abdalhamid, Joshua M. Tebbs and Christopher S. McMahan explain how, by pooling specimens, testing capacity for SARS-CoV-2 can be increased.

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Figures

FIGURE 1
FIGURE 1
Reduction in the expected number of tests for group testing algorithms. Group sizes chosen are those that minimise the expected number of tests per individual at a particular disease prevalence and for a specific algorithm. The maximum group size allowed is 40. The right-hand-side y-axis displays the expected increase in the testing capacity (see box, below) relative to the tick marks on the left-hand-side y-axis.
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See this image and copyright information in PMC

References

    1. Dorfman R. (1943) The detection of defective members of large populations. Annals of Mathematical Statistics, 14, 436–440.
    1. Lewis, J., Lockary, V. and Kobic, S. (2012) Cost savings and increased efficiency using a stratified specimen pooling strategy for Chlamydia trachomatis and Neisseria gonorrhoeae. Sexually Transmitted Diseases, 39, 46–48. - PubMed
    1. Græsb⊘ll, K., Andresen, L., Halasa, T. and Toft, N. (2017) Opportunities and challenges when pooling milk samples using ELISA. Preventative Veterinary Medicine, 139, 93–98. - PubMed
    1. Salzer, E., Nixon, E., Drewes, G., Reinhard, F., Bergamini, G. and Rau, C. (2016) Screening pools of compounds against multiple endogenously expressed targets in a chemoproteomics binding assay. Journal of Laboratory Automation, 21, 133–142. - PubMed
    1. Van, T., Miller, J., Warshauer, D., Reisdorf, E., Jernigan, D., Humes, R. and Shult, P. (2012) Pooling nasopharyngeal/throat swab specimens to increase testing capacity for influenza viruses by PCR. Journal of Clinical Microbiology, 50, 891–896. - PMC - PubMed

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