Hospital-Wide SARS-CoV-2 Antibody Screening in 3056 Staff in a Tertiary Center in Belgium

Abstract

This study characterizes the prevalence of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among hospital staff of a Belgian tertiary care center tested over 1 week in April 2020, and risk factors for seropositivity.

Figure 1.. Epidemic Timeline of Patients With COVID-19 Admitted to Hospital East-Limburg, Belgium, 2020

The epidemic curve is shown as the number of patients with coronavirus disease 2019 (COVID-19) admitted at the institution each day. The first case was detected March 13. Serosurvey of staff was initiated from April 22, 2020, to April 30, 2020. Details of the infection prevention measures are depicted below the curve. FFP indicates filtering facepiece; RT-PCR, reverse transcriptase–polymerase chain reaction; TAT, turnaround time.

Figure 2.. Exposure and Symptomatology Predictors of SARS-CoV-2 Antibodies Among Staff, Hospital East-Limburg, Belgium, 2020

A, 95% CIs of the odds ratios based on bivariable logistic regression analyses. B, 95% CIs of the odds ratios based on multivariable (with all symptoms included in the model) logistic regression analyses. SARS-CoV-2 indicates severe acute respiratory syndrome coronavirus 2. ^aFever could be either subjective or confirmed.