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Case Reports
. 2020 Nov;33(6):e13834.
doi: 10.1111/dth.13834. Epub 2020 Jul 8.

Acute generalized exanthematous pustulosis induced by empiric hydroxychloroquine for presumed COVID-19

Tyler Enos  1 , Haneol S Jeong  1 , Travis Vandergriff  1 , Heidi T Jacobe  1 , Benjamin F Chong  1
Affiliations
Case Reports

Acute generalized exanthematous pustulosis induced by empiric hydroxychloroquine for presumed COVID-19

Tyler Enos et al. Dermatol Ther. 2020 Nov.
No abstract available

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Conflict of interest statement

The authors declare no potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Patient's Rash. Red‐pink erythematous papules and non‐follicular pustules involving, A, face and B, abdomen. C, Close up of pinpoint pustules. Informed consent was obtained from the patient to publish these photos
FIGURE 2
FIGURE 2
Skin biopsy pathology. A, Hematoxylin‐eosin stained punch biopsy from the abdomen showing a ruptured subcorneal pustule (100× magnification); B, with neutrophils and eosinophils consistent with acute generalized exanthematous pustulosis (400× magnification)
See this image and copyright information in PMC

References

    1. Szatkowsk J, Schwartz RA. Acute generalized exanthematous pustulosis (AGEP): a review and update. J Am Acad Dermatol. 2015;73:843‐848. - PubMed
    1. Evans CC, Bergstresser PR. Acute generalized exanthematous pustulosis precipitated by hydroxychloroquine. J Am Acad Dermatol. 2004;50:650‐651. - PubMed
    1. Sharma AN, Mesinkovska NA, Paravar T. Characterizing the adverse dermatologic effects of hydroxychloroquine: a systematic review. J Am Acad Dermatol. 2020;S0190‐9622(20)30564‐8 [published online ahead of print, 2020 Apr 11]. 10.1016/j.jaad.2020.04.02. - DOI - PubMed
    1. Castner NB, Harris JC, Motaparthi K. Cyclosporine for corticosteroid‐refractory acute generalized exanthematous pustulosis due to hydroxychloroquine. Dermatol Ther. 2018;31(5):e12660. - PubMed
    1. Pearson KC, Morrell DS, Runge SR, Jolly P. Prolonged pustular eruption from hydroxychloroquine: an unusual case of acute generalized exanthematous pustulosis. Cutis. 2016;97(3):212‐216. - PubMed

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