TMEM106B, an unexpected point of contact between FTD, ageing and a hypomyelination disorder

James J Doyle^{1

2}, J Alex Parker¹, Andrew Bateman²

Affiliations

¹ Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Department of Neuroscience, Université de Montréal, Quebec, Canada.
² Division of Experimental Medicine, Department of Medicine, McGill University, Montréal, Quebec, Canada.

Comment

James J Doyle et al. Brain. 2020.

. 2020 Jun 1;143(6):1628-1631.

doi: 10.1093/brain/awaa149.

James J Doyle^{1

2}, J Alex Parker¹, Andrew Bateman²

¹ Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Department of Neuroscience, Université de Montréal, Quebec, Canada.
² Division of Experimental Medicine, Department of Medicine, McGill University, Montréal, Quebec, Canada.

No abstract available

Comment on

Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies.
Zhou X, Nicholson AM, Ren Y, Brooks M, Jiang P, Zuberi A, Phuoc HN, Perkerson RB, Matchett B, Parsons TM, Finch NA, Lin W, Qiao W, Castanedes-Casey M, Phillips V, Librero AL, Asmann Y, Bu G, Murray ME, Lutz C, Dickson DW, Rademakers R. Zhou X, et al. Brain. 2020 Jun 1;143(6):1905-1919. doi: 10.1093/brain/awaa141. Brain. 2020. PMID: 32504082 Free PMC article.