Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Oct 20;173(8):654-655.
doi: 10.7326/M20-3775. Epub 2020 Jun 16.

Promoting Better Clinical Trials and Drug Information as Public Health Interventions for the COVID-19 Emergency in Italy

Antonio Addis  1 , Armando Genazzani  2 , Maria Paola Trotta  3 , Nicola Magrini  3 ; Italian Medicines Agency's Scientific Committee and COVID-19 Crisis Unit
Collaborators, Affiliations
Editorial

Promoting Better Clinical Trials and Drug Information as Public Health Interventions for the COVID-19 Emergency in Italy

Antonio Addis et al. Ann Intern Med. .

Abstract

According to these authors from the Italian Medicines Agency, “evidence-informed prescribing and clinical trials were beaten off the mark by social media, rumors, and panic in the early phase of the COVID-19 pandemic.” In this article, they describe lessons learned to counteract misleading information and nudge the research community to do high-quality, informative multigroup trials.

PubMed Disclaimer

References

    1. Kalil AC. Treating COVID-19—off-label drug use, compassionate use, and randomized clinical trials during pandemics. JAMA. 2020. [PMID: 32208486] doi:10.1001/jama.2020.4742. - PubMed
    1. Rome BN, Avorn J. Drug evaluation during the Covid-19 pandemic. N Engl J Med. 2020;382:2282-2284. [PMID: 32289216] doi:10.1056/NEJMp2009457. - PubMed
    1. Fauci AS, Lane HC, Redfield RR. Covid-19—navigating the uncharted [Editorial]. N Engl J Med. 2020;382:1268-1269. [PMID: 32109011] doi:10.1056/NEJMe2002387. - PMC - PubMed
    1. London AJ, Kimmelman J. Against pandemic research exceptionalism. Science. 2020;368:476-477. [PMID: 32327600] doi:10.1126/science.abc1731. - PubMed
    1. Decreto Legge Cura Italia Art. 17. Disposizioni urgenti materia di sperimentazione dei medicinali e dispositivi medici per l'emergenza epidemiologica da COVID. Gazzetta Ufficiale (serie generale n.70 del 17-03-2020). Accessed at www.gazzettaufficiale.it/eli/gu/2020/03/17/70/sg/pdf. on 16 June 2020.

Publication types