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. 2020 May 19;7(6):ofaa167.
doi: 10.1093/ofid/ofaa167. eCollection 2020 Jun.

Coccidioidomycosis in Patients Treated With Ruxolitinib

Yael Kusne  1 , Kathryn E Kimes  2 , Fionna F Feller  1 , Roberto Patron  2 , Juan Gea Banacloche  2 , Janis E Blair  2 , Holenarasipur R Vikram  2 , Neil M Ampel  2
Affiliations

Coccidioidomycosis in Patients Treated With Ruxolitinib

Yael Kusne et al. Open Forum Infect Dis. .

Abstract

We report 8 cases of coccidioidomycosis associated with ruxolitinib treatment. Among 135 patients living in the coccidioidal-endemic region receiving ruxolitinib, 5 cases were diagnosed after starting and 4 had extrathoracic dissemination. Periodic serological screening while on ruxolitinib is warranted for patients residing in the coccidioidal-endemic region.

Keywords: coccidioidomycosis; fungal infections; immunocompromised host; ruxolitinib.

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