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Case Reports
. 2020 Apr 26:33:100575.
doi: 10.1016/j.gore.2020.100575. eCollection 2020 Aug.

Paraneoplastic Raynaud phenomenon associated with metastatic ovarian cancer: A case report and review of the literature

Tiffany S Lai  1 , Man R Shim  2 , David Shin  3 , Mae Zakhour  1
Affiliations
Case Reports

Paraneoplastic Raynaud phenomenon associated with metastatic ovarian cancer: A case report and review of the literature

Tiffany S Lai et al. Gynecol Oncol Rep. .

Abstract

•Paraneoplastic syndromes are rarely associated with ovarian malignancies.•Paraneoplastic syndromes may be the presenting symptom of an underlying malignancy.•Rheumatologic disorders with unusual presentations may be malignancy related.•These rheumatologic disorders are often refractory to standard treatments.

Keywords: Ovarian cancer; Paraneoplastic syndromes; Rheumatologic disorders.

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Conflict of interest statement

The authors declared that there is no conflict of interest.

Figures

Fig. 1
Fig. 1
Prior to the diagnosis of ovarian cancer, patient developed Raynaud’s syndrome associated with digital ulcerations, which was refractory to multiple treatments.
Fig. 2
Fig. 2
Raynaud’s syndrome resolved three weeks following optimal cytoreduction for ovarian cancer, prior to the initiation of chemotherapy.
See this image and copyright information in PMC

References

    1. Block J., Sequeira W. Raynaud’s phenomenon. Lancet. 2001;357:2042–2048. - PubMed
    1. Cherin P., Piette J.C., Herson S., Bletry O., Wechsler B., Frances C., Godeau P. J. Rheumatol. 1993;20(11):1897–1899. - PubMed
    1. Dieffenbach C., Bouberhan S., Raynor E., Shea M., Liu F. Polymyositis as a presentation of advanced carcinoma of Mullerian origin: a case report and discussion. Gynecol. Oncol. Rep. 2018;25:1–2. - PMC - PubMed
    1. Hawley P.R., Johnston A.W., Rankin J.T. Association between digital ischemia and malignant disease. Br. Med. J. 1967;3:208–211. - PMC - PubMed
    1. Herrick A. Evidence-based management of Raynaud’s phenomenon. Ther. Adv. Musculoskel. Dis. 2017;9(12):317–329. - PMC - PubMed

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