Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 May;9(3):152-163.
doi: 10.21037/acs.2020.03.13.

Frozen elephant trunk with Frozenix prosthesis

Yutaka Okita  1   2
Affiliations
Review

Frozen elephant trunk with Frozenix prosthesis

Yutaka Okita. Ann Cardiothorac Surg. 2020 May.

Abstract

This paper presents the clinical applications of the Japanese-made frozen elephant trunk (FET, Frozenix®). The historical aspects of FET development, manufacture and structure of Frozenix, video images of a representative case, and a summary of a multi-centre Japanese Frozenix study, J-ORCHESTRA, are discussed.

Keywords: Total arch replacement; acute aortic dissection; brain malperfusion; distal aortic aneurysm; frozen elephant trunk (FET); selective antegrade cerebral perfusion.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Open arch surgery in Japan, JATS survey. (A) Elective surgery for the aortic arch, (B) surgery for acute type A aortic dissection.
Figure 2
Figure 2
Arch surgery in Japan excluding acute aortic dissection, ruptured aneurysm, JCVSD (Japanese Cardiovascular Surgery Database) database: 2015–2016.
Figure 3
Figure 3
Frozenix®, graft fabric and internal skeleton.
Figure 4
Figure 4
Frozenix® in the market for Acute Aortic Dissection, (A) graft size, length, (B) graft size, diameter.
Figure 5
Figure 5
Frozenix® in the market for Non-dissecting Aneurysm, (A) graft size, length, (B) graft size, diameter.
Figure 6
Figure 6
Aortic lesions in J-ORCHESTRA, (A) FET group, (B) non-FET group.
Figure 7
Figure 7
Location of FET tip, distal anastomosis.
Figure 8
Figure 8
Zone tip. Red triangle; patients with acute aortic dissection complicated with spinal cord injury, yellow triangle; patients with non-dissection complicated with spinal cord injury.
Figure 9
Figure 9
Circulatory arrest time of the lower body. Red triangle; patients with acute aortic dissection complicated with spinal cord injury, yellow triangle; patients with non-dissection complicated with spinal cord injury.
Figure 10
Figure 10
Minimum body temperature. Red triangle; patients with acute aortic dissection complicated with spinal cord injury, yellow triangle; patients with non-dissection complicated with spinal cord injury.
Video
Video
Frozen elephant trunk with Frozenix prosthesis.
See this image and copyright information in PMC

References

    1. Kato M, Ohnishi K, Kaneko M, et al. New graft-implanting method for thoracic aortic aneurysm or dissection with a stented graft. Circulation 1996;94:II188-93. - PubMed
    1. Karck M, Chavan A, Hagl C, et al. The frozen elephant trunk technique: a new treatment for thoracic aortic aneurysms. J Thorac Cardiovasc Surg. 2003;125:1550-3. 10.1016/S0022-5223(03)00045-X - DOI - PubMed
    1. Easo J, Weigang E, Holzl PP, et al. Influence of operative strategy for the aortic arch in DeBakey type I aortic dissection: analysis of the German Registry for Acute Aortic Dissection Type A. J Thorac Cardiovasc Surg 2012;144:617-23. 10.1016/j.jtcvs.2011.07.066 - DOI - PubMed
    1. Jakob H, Dohle D, Benedik J, et al. Long-term experience with the E-vita Open hybrid graft in complex thoracic aortic disease. Eur J Cardiothorac Surg 2017;51:329-38. - PubMed
    1. Czerny M, Barchichat I, Meszaros K, et al. Long-term results after proximal thoracic aortic redo surgery. PLoS One 2013;8:e57713. 10.1371/journal.pone.0057713 - DOI - PMC - PubMed