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Comment
. 2020 Jun 16;52(6):902-904.
doi: 10.1016/j.immuni.2020.05.012.

Exercising Immunity: Interleukin-13 Flexes Muscle

Lauren M Webb  1 , Elia D Tait Wojno  2
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Free article
Comment

Exercising Immunity: Interleukin-13 Flexes Muscle

Lauren M Webb et al. Immunity. .
Free article

Abstract

Endurance exercise drives physiological changes in the muscle to optimize performance. In a recent study in Science, Knudsen et al. report a role for the type 2 cytokine interleukin-13 in orchestrating metabolic reprogramming that drives adaptation to endurance exercise.

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  • Interleukin-13 drives metabolic conditioning of muscle to endurance exercise.
    Knudsen NH, Stanya KJ, Hyde AL, Chalom MM, Alexander RK, Liou YH, Starost KA, Gangl MR, Jacobi D, Liu S, Sopariwala DH, Fonseca-Pereira D, Li J, Hu FB, Garrett WS, Narkar VA, Ortlund EA, Kim JH, Paton CM, Cooper JA, Lee CH. Knudsen NH, et al. Science. 2020 May 1;368(6490):eaat3987. doi: 10.1126/science.aat3987. Epub 2020 Apr 30. Science. 2020. PMID: 32355002 Free PMC article.

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