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. 2020 Aug:97:371-373.
doi: 10.1016/j.ijid.2020.06.014. Epub 2020 Jun 14.

Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19: Insights from simultaneous familial Kawasaki Disease cases

R Ebina-Shibuya  1 , H Namkoong  2 , Y Shibuya  3 , N Horita  4
Affiliations

Multisystem Inflammatory Syndrome in Children (MIS-C) with COVID-19: Insights from simultaneous familial Kawasaki Disease cases

R Ebina-Shibuya et al. Int J Infect Dis. 2020 Aug.

Abstract

Recently, an increasing number of SARS-CoV-2 patients with COVID-19 syndrome, which overlaps with Kawasaki Disease (KD), have been reported, supporting the suggestion that infection is one of the triggers of KD. We summarized the reports of simultaneous familial KD cases to better understand the etiopathogenesis of both KD and Multisystem Inflammatory Syndrome in Children (MIS-C) related to COVID-19. Here we discuss the etiology of these syndromes from the point of view of infection and genetic susceptibility.

Keywords: COVID-19; Kawasaki Disease; Multisystem Inflammatory Syndrome in Children (MIS-C); SARS-CoV-2.

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References

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Supplementary concepts