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Comment
. 2020 Aug 13;56(2):2001610.
doi: 10.1183/13993003.01610-2020. Print 2020 Aug.

Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors and beyond

Senad Hasanagic  1 , Fadila Serdarevic  2
Affiliations
Comment

Potential role of memantine in the prevention and treatment of COVID-19: its antagonism of nicotinic acetylcholine receptors and beyond

Senad Hasanagic et al. Eur Respir J. .

Abstract

Memantine, as an antagonist of α7-nAChR and NMDA receptors, may decrease ACE2 receptor expression and reduce oxidative stress and inflammation. Hence, memantine may potentially reduce SARS-CoV-2 virulence. https://bit.ly/2AZHiVg

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Conflict of interest statement

Conflict of interest: S. Hasanagic has nothing to disclose. Conflict of interest: F. Serdarevic has nothing to disclose.

Comment on

References

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