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Comment
. 2020 Aug;190(4):e187-e189.
doi: 10.1111/bjh.16954. Epub 2020 Jul 9.

Unexpected kinetics of anti-SARS-CoV-2 total antibodies in two patients with chronic lymphocytic leukemia

Julien Favresse  1   2 , Christine Eucher  1 , Marc Elsen  1 , Carlos Graux  3 , Paul Goebels  4 , Kim Laffineur  1 , Jean-Baptiste Nicolas  5 , Jean-Michel Dogné  2 , Jonathan Douxfils  2   6
Affiliations
Comment

Unexpected kinetics of anti-SARS-CoV-2 total antibodies in two patients with chronic lymphocytic leukemia

Julien Favresse et al. Br J Haematol. 2020 Aug.
No abstract available

Keywords: COVID-19; SARS-CoV-2; kinetics; serology; symptom onset.

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Conflict of interest statement

Among the authors, Jonathan Douxfils is chief executive officer and founder of QUALIblood sa and reports personal fees from Diagnostica Stago, Roche, Roche Diagnostics, Daiichi‐Sankyo and Portola, outside the submitted work. Roche Diagnostics generously provided the kits for the validation.

Figures

Fig 1
Fig 1
(A) Seroconversion in 11 patients with serial samples (one colour per patient). Optimized cut‐off (i.e. >0·165) and the limit of quantification (LOQ) of the assay (i.e. >0·151) are represented with black‐ and grey‐dotted lines respectively. (B) Lymphocyte kinetics in 11 patients with serial samples (one colour per patient) from reverse transcription polymerase chain reaction (RT‐PCR) positivity. Reference interval is represented with black dotted lines.
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