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Editorial
. 2020 Jul;108(1):9-11.
doi: 10.1002/JLB.5CE0520-108R. Epub 2020 Jun 18.

Divergent Siglec-F(eights) of mouse and human eosinophil death

Elizabeth A Jacobsen  1
Affiliations
Editorial

Divergent Siglec-F(eights) of mouse and human eosinophil death

Elizabeth A Jacobsen. J Leukoc Biol. 2020 Jul.

Abstract

Discussion on the differences between mouse and human eosinophil induced death by antibody ligation to human Siglec-8 and mouse Siglec-F.

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Figures

Figure :
Figure :. Siglec-8 and Siglec-F Antibodies for Detection and Depletion of Human and Mouse Eosinophils.
* Human data is shown for comparison and is acquired from the bibliography.
See this image and copyright information in PMC

Comment on

References

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    1. Knuplez E, Krier-Burris R, Cao Y, Marsche G, O’Sullivan J, and Bochner BS, Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls. J Leukoc Biol, 2020. - PMC - PubMed
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    1. Na HJ, Hudson SA, and Bochner BS, IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils. Cytokine, 2012. 57(1): p. 169–74. - PMC - PubMed

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