Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Jul;35(7):1137.
doi: 10.1002/mds.28122. Epub 2020 Jun 19.

Timing Is Everything: The T-Cell Response to α-Synuclein Is Maximal in Early Parkinson's

Antonina Kouli  1 , Caroline H Williams-Gray  1
Affiliations
Comment

Timing Is Everything: The T-Cell Response to α-Synuclein Is Maximal in Early Parkinson's

Antonina Kouli et al. Mov Disord. 2020 Jul.
No abstract available

Keywords: Parkinson's disease; T cells; immune system; α-synuclein.

PubMed Disclaimer

Comment on

References

    1. Schonhoff AM, Williams GP, Wallen ZD, et al. Innate and adaptive immune responses in Parkinson's disease. Prog Brain Res 2020;252:169-216. doi: https://doi.org/10.1016/bs.pbr.2019.10.006
    1. Saiki M, Baker A, Williams-Gray CH, et al. Association of the human leucocyte antigen region with susceptibility to Parkinson's disease. J Neurol Neurosur Ps 2010;81(8):890-1.
    1. Sulzer D, Alcalay RN, Garretti F, et al. T cells from patients with Parkinson's disease recognize alpha-synuclein peptides. Nature 2017;546(7660):656-61. doi: https://doi.org/10.1038/nature22815
    1. Lindestam Arlehamn CS, Dhanwani R, Pham J, et al. alpha-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease. Nat Commun 2020;11(1):1875. doi: https://doi.org/10.1038/s41467-020-15626-w
    1. Scott KM, Kouli A, Yeoh SL, et al. A systematic review and meta-analysis of alpha synuclein auto-antibodies in Parkinson's disease. Front Neurol 2018;9(815) doi: https://doi.org/10.3389/fneur.2018.00815

Substances

LinkOut - more resources