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Comment
. 2020 Jul;69(7):1336-1338.
doi: 10.2337/dbi20-0016.

Blood Flow in the Pancreatic Islet: Not so Isolated Anymore

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Comment

Blood Flow in the Pancreatic Islet: Not so Isolated Anymore

Joana Almaça et al. Diabetes. 2020 Jul.
No abstract available

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Figures

Figure 1
Figure 1
Cartoons depicting three different models of blood flow in the pancreas. Until recently, the microcirculation of the islet was considered to be independent of that of the surrounding exocrine tissues (left). In an article published in this issue of Diabetes, Dybala et al. (6) now show that the circulation of the islet is integrated with that of the exocrine tissue, with blood flowing bidirectionally between both compartments (center). In a more sophisticated model, regulatory elements such as nervous input and vascular gates can be incorporated into this scheme to allow for local control of blood flow (right).

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References

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