Management of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH)
- PMID: 32562297
- DOI: 10.1111/tbj.13950
Management of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH)
Abstract
Pseudoangiomatous stromal hyperplasia (PASH) is a benign hyperplastic condition of the breast that can lead to macromastia. The standard treatment for PASH is focal excision or rarely reduction mammoplasty. We present a rare case of postpartum bilateral rapid breast enlargement and axillary growth that was refractory to reduction mammoplasty. Ultimately, the patient required bilateral mastectomy and two-stage implant-based breast reconstruction. This more extensive form along with its management represents one of the few reported cases in the literature. The decision to pursue bilateral mastectomy was undertaken after exhausting more conservative options. Excellent aesthetic outcome and pain relief was obtained following definitive extirpative and reconstructive surgery.
Keywords: breast hyperplasia; mastectomy; pseudoangiomatous stromal hyperplasia.
© 2020 Wiley Periodicals LLC.
References
REFERENCES
-
- Vuitch MF, Rosen PP, Erlandson RA. Pseudoangiomatous hyperplasia of mammary stroma. Hum Pathol. 1986;17(2):185-191.
-
- Ibrahim RE, Sciotto CG, Weidner N. Pseudoangiomatous hyperplasia of mammary stroma. Some observations regarding its clinicopathologic spectrum. Cancer. 1989;63(6):1154-1160.
-
- Singh KA, Lewis MM, Runge RL, Carlson GW. Pseudoangiomatous stromal hyperplasia. A case for bilateral mastectomy in a 12-year-old girl. Breast J. 2007;13(6):603-606.
-
- Powell CM, Cranor ML, Rosen PP. Pseudoangiomatous stromal hyperplasia (PASH). A mammary stromal tumor with myofibroblastic differentiation. Am J Surg Pathol. 1995;19(3):270-277.
-
- Prichard RS, O'Neill CJ, O'Hara JL, Atmore BB, Hassall M. Pseudoangiomatous stromal hyperplasia of the breast: an unusual pathology necessitating bilateral mastectomy during pregnancy. ANZ J Surg. 2011;81(4):304-305.
Publication types
MeSH terms
Supplementary concepts
LinkOut - more resources
Full Text Sources
Medical