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Comment
. 2020 Sep;81(3):452-482.
doi: 10.1016/j.jinf.2020.06.034. Epub 2020 Jun 18.

Low transmission risk of 9 asymptomatic carriers tested positive for both SARS-CoV-2 nucleic acid and serum IgG

Fenghua Chen  1 , Daan Fu  2 , Qianqian Yang  1 , Zhi Geng  1 , Jiahong Xia  3 , Zheng Wang  4 , Lin Wang  5
Affiliations
Comment

Low transmission risk of 9 asymptomatic carriers tested positive for both SARS-CoV-2 nucleic acid and serum IgG

Fenghua Chen et al. J Infect. 2020 Sep.

Abstract

  1. •

    Asymptomatic carriers (RT-PCR+ and serum IgG+) are unable to transmit virus.

  2. •

    Such a low transmission risk might be partly associated with high Ct values.

  3. •

    A new pattern in SARS-CoV-2 infected patients might have emerged.

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Figures

Fig. 1
Fig. 1
Timeline of nine asymptomatic carriers with SARS-CoV-2-specific IgG positive.
See this image and copyright information in PMC

Comment on

References

    1. Huang L., Zhang X., Zhang X., Wei Z., Zhang L., Xu J. Rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16–23 years outside Wuhan and characteristics of young patients with COVID-19: a prospective contact-tracing study. J Infect. 2020;80(6):e1‐e13. doi: 10.1016/j.jinf.2020.03.006. - DOI - PMC - PubMed
    1. WHO. Novel coronavirus (COVID-19) situation. Updated May 30, 2020. https://www.who.int/docs/default-source/coronaviruse/situation-reports/2....
    1. Chan J.F., Yuan S., Kok K.H., To K.K., Chu H., Yang J. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395(10223):514‐523. doi: 10.1016/S0140-6736(20)30154-9. - DOI - PMC - PubMed
    1. Bai Y., Yao L., Wei T., Tian F., Jin D.Y., Chen L. Presumed asymptomatic carrier transmission of COVID-19 [published online ahead of print, 2020 Feb 21] JAMA. 2020;323(14):1406‐1407. doi: 10.1001/jama.2020.2565. - DOI - PMC - PubMed
    1. Hu Z., Song C., Xu C., Jin G., Chen Y., Xu X. et al. Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China. Sci China Life Sci. 2020;63(5):706‐711. doi: 10.1007/s11427-020-1661-4. - DOI - PMC - PubMed

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