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Review
. 2020 Apr;30(Suppl 1):S11-S16.
doi: 10.4103/jcecho.jcecho_3_19. Epub 2020 Apr 10.

Vascular Damage - Coronary Artery Disease

Christian Cadeddu Dessalvi  1 , Martino Deidda  1 , Mauro Giorgi  2 , Paolo Colonna  3
Affiliations
Review

Vascular Damage - Coronary Artery Disease

Christian Cadeddu Dessalvi et al. J Cardiovasc Echogr. 2020 Apr.

Abstract

Cardiovascular complications during chemotherapy and radiotherapy are becoming an increasing problem because many patients with cancer are treated with agents that exert significant vascular toxicity. Coronary heart disease in patients with cancer presents particular challenges, which directly impact the management of both the coronary disease and malignancy. Several chemotherapeutic agents have been shown to trigger ischemic heart disease, and as it has happened for myocardial cardiotoxicity, more attention should be dedicated to improving early recognition and prevention of cardiac vascular toxicity. Cardiac imaging could facilitate early detection of vascular toxicity, but a thorough risk stratification should always be performed to identify patients at higher risk of vascular impairment.

Keywords: Cardiotoxicity; coronary artery disease; echocardiography; vascular toxicity.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
The main mechanism of chemotherapy-induced vascular toxicity
See this image and copyright information in PMC

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