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Review
. 2020 Jul;48(3):133-139.
doi: 10.1249/JES.0000000000000223.

L-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults

Arturo Figueroa  1 , Salvador J Jaime  2 , Masahiko Morita  3 , Joaquin U Gonzales  1 , Christophe Moinard  4
Affiliations
Review

L-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults

Arturo Figueroa et al. Exerc Sport Sci Rev. 2020 Jul.

Abstract

Age-associated reduction in endothelial nitric oxide (NO) synthesis contributes to the development of cardiovascular diseases and sarcopenia. L-Citrulline is a precursor of NO with the ability to improve vascular function and muscle protein synthesis. We hypothesize that vascular and muscular benefits associated with oral L-citrulline supplementation might be augmented by concomitant supplementation with exercise training in older adults.

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