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Comment
. 2020 Sep;81(3):e82-e84.
doi: 10.1016/j.jinf.2020.06.036. Epub 2020 Jun 20.

CD4+T, CD8+T counts and severe COVID-19: A meta-analysis

Affiliations
Comment

CD4+T, CD8+T counts and severe COVID-19: A meta-analysis

Haipeng Zhang et al. J Infect. 2020 Sep.
No abstract available

Keywords: CD4+T; CD4/CD8 ratio; CD8+T; COVID-19; Meta-analysis.

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Figures

Fig 1
Fig. 1
Mean difference (MD) and 95% confidence interval (95% CI) of counts of CD4+T, CD8+T and CD4/CD8 ratio in COVID-19 patients with or without severe disease. A, CD4+T. B, CD8+T. C, CD4/CD8 ratio.

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References

    1. Liu Z., Long W., Tu M. Lymphocyte subset (CD4+, CD8+) counts reflect the severity of infection and predict the clinical outcomes in patients with COVID-19. J Infect. 2020 doi: 10.1016/j.jinf.2020.03.054. - DOI - PMC - PubMed
    1. Jiang M., Guo Y., Luo Q. T cell subset counts in peripheral blood can be used as discriminatory biomarkers for diagnosis and severity prediction of COVID-19. J Infect Dis. 2020 doi: 10.1093/infdis/jiaa252. - DOI - PMC - PubMed
    1. National Health Commission of the People's Republic of China. Guidelines for the Diagnosis and Treatment of COVID-19 (Trial Version 7). 2020.http://www.nhc.gov.cn/yzygj/s7653p/202003/46c9294a7dfe4cef80dc7f5912eb19.... Accessed Jun 16,2020.
    1. Urra J.M., Cabrera C.M., Porras L. Selective CD8 cell reduction by SARS-CoV-2 is associated with a worse prognosis and systemic inflammation in COVID-19 patients. Clin Immunol (Orlando, Fla) 2020 doi: 10.1016/j.clim.2020.108486. - DOI - PMC - PubMed
    1. Diao B., Wang C., Tan Y. Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) Clin Transl Immunol. 2020;11:827. doi: 10.1002/cti2.112810.3389/fimmu.2020.00827. - DOI - PMC - PubMed