Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep;360(3):301-303.
doi: 10.1016/j.amjms.2020.05.033. Epub 2020 May 28.

SARS-CoV-2 Infection: Beyond the Interstitial Pneumonia

Affiliations
Comment

SARS-CoV-2 Infection: Beyond the Interstitial Pneumonia

Ran Cui et al. Am J Med Sci. 2020 Sep.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Laboratory parameters in case 1 and 3 and computed tomography (CT) images of three cases. Case 1: timeline charts illustrated leukocytosis, lymphopenia and a high D-dimer concentration (1A-C). The first CTs of chest and brain were obtained on day 12 after the onset of illness. Chest CT showed bilateral multiple mottling and ground-glass opacity. Condensation shadows were observed in the lower right lobe (1D). The CT of the brain showed right frontal lobe infarction with hemorrhagic transformation (1E, yellow arrow). The second chest CT revealed a cavity in condensation shadows in the lower right lobe (1F). Case 2: the first and second chest CTs were obtained on day 1 and 4 after the admission, respectively. A cavitation with fluid level inside was observed in right middle lobe (2A, yellow asterisk). The red arrow indicated closed drainage tube. The second chest CT showed that the lung abscess was fading gradually (2B). Case 3: timeline charts illustrated the elevated serum concentrations of amylase and lipase. On the day 5 after the onset of abdominal pain, the serum concentrations of amylase and lipase reached the peak (3A). The abdomen CT showed edema pancreatitis (3B, red arrows).

Comment on

References

    1. Pan L, Mu M, Yang P. Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study. Am J Gastroenterol. 2020;115(5):766–773. - PMC - PubMed
    1. Walls AC, Park YJ, Tortorici MA. Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein. Cell. 2020;181(2):281–292. - PMC - PubMed
    1. Huang C, Wang Y, Li X. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. - PMC - PubMed
    1. Yan R, Zhang Y, Li Y. Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2. Science. 2020;367(6485):1444–1448. - PMC - PubMed
    1. Kuba K, Imai Y, Ohto-Nakanishi T. Trilogy of ACE2: a peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters. Pharmacol Ther. 2010;128(1):119–128. - PMC - PubMed