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. 2020 May 19:11:1021.
doi: 10.3389/fimmu.2020.01021. eCollection 2020.

Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19

Adnan Shah  1
Affiliations

Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19

Adnan Shah. Front Immunol. .
No abstract available

Keywords: COVID-19; NLRP3 inflammasome; SARS-CoV; cytokines; viroporins.

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Figures

Figure 1
Figure 1
Schematic representation of SARS-CoV viroporin-mediated NLRP3 inflammasome activation, its inhibitors (shown with asterisks) and downstream inflammatory cascades leading to inflammation and cell death. Genes (italicized) in empty boxes, respective proteins in gray boxes.
See this image and copyright information in PMC

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