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Case Reports
. 2020 Jun 22:53:e20200040.
doi: 10.1590/0037-8682-0040-2020. eCollection 2020.

Mucocutaneous leishmaniasis in a cocaine user: diagnostic and therapeutic knowledge

Lissiê Lunardi Sbroglio  1 , Viviane Maria Maiolini  1 , Irene Machado Moraes Alvarenga Rabelo  1 , Gabriela Almeida Giraldelli  2 , Luciana Patrícia Tuccori  3 , Rodrigo Guimarães Cunha  4
Affiliations
Case Reports

Mucocutaneous leishmaniasis in a cocaine user: diagnostic and therapeutic knowledge

Lissiê Lunardi Sbroglio et al. Rev Soc Bras Med Trop. .

Abstract

Mucocutaneous leishmaniasis (MCL) is a chronic infection that can affect the skin and mucous membranes. We report a case of oral, nasopharyngeal, and penile lesions in a 35-year-old cocaine user. The patient presented with ulcerated lesions in 2014. Histopathologic analysis revealed amastigotes, and serological test results were positive for leishmaniasis. Systemic therapy with meglumine antimoniate was administered; however, the patient failed to present for follow-up. In 2018, he returned with nasal collapse, and another histopathologic test confirmed MCL. This case illustrates the importance of careful differential diagnosis of skin and mucous ulcers to identify the particular pathology.

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Conflict of interest statement

Conflicts of Interest: The authors declare that there are no conflicts of interest.

Figures

FIGURE 1:
FIGURE 1:. Characteristic ulcerated lesion with exudation and infiltration in the nasal base, filter, palate, and balanoprepucial sulcus.
FIGURE 2:
FIGURE 2:. Nasal collapse on the right.
FIGURE 3:
FIGURE 3:. Histopathological examination results of the nasal mucosa, showing acute and chronic ulcerated inflammatory processes with giant cell reaction (Langerhans cells) and epithelioid histocytes, compatible with a diagnosis of leishmaniasis.
See this image and copyright information in PMC

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