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. 2020 Sep 1;59(5):458-468.
doi: 10.30802/AALAS-JAALAS-20-000008. Epub 2020 Jun 24.

PCR and RT-PCR in the Diagnosis of Laboratory Animal Infections and in Health Monitoring

Susan R Compton  1
Affiliations

PCR and RT-PCR in the Diagnosis of Laboratory Animal Infections and in Health Monitoring

Susan R Compton. J Am Assoc Lab Anim Sci. .

Abstract

Molecular diagnostics (PCR and RT-PCR) have become commonplace in laboratory animal research and diagnostics, augmenting or replacing serological and microbiologic methods. This overview will discuss the uses of molecular diagnostics in the diagnosis of pathogenic infections of laboratory animals and in monitoring the microbial status of laboratory animals and their environment. The article will focus primarily on laboratory rodents, although PCR can be used on samples from any laboratory animal species.

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Figures

Figure 1.
Figure 1.
Infectious agents recommended for monitoring in mice and rats.
Figure 2.
Figure 2.
Laboratory animal infectious agent detection methods.
See this image and copyright information in PMC

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