Doesn't It All Come Down to Function? How To Correlate VAR2CSA Antibodies with Protection
- PMID: 32581073
- PMCID: PMC7316495
- DOI: 10.1128/mSphere.00521-20
Doesn't It All Come Down to Function? How To Correlate VAR2CSA Antibodies with Protection
Keywords: Plasmodium falciparum; VAR2CSA antibodies; malaria; men and children; pregnancy.
Comment on
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mSphere of Influence: Going Native, or the Risk of Overreliance on Recombinant Antigens.mSphere. 2020 Apr 8;5(2):e00224-20. doi: 10.1128/mSphere.00224-20. mSphere. 2020. PMID: 32269160 Free PMC article.
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References
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- O'Neil-Dunne I, Achur RN, Agbor-Enoh ST, Valiyaveettil M, Naik RS, Ockenhouse CF, Zhou A, Megnekou R, Leke R, Taylor DW, Gowda DC. 2001. Gravidity-dependent production of antibodies that inhibit binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate proteoglycan during pregnancy. Infect Immun 69:7487–7492. doi:10.1128/IAI.69.12.7487-7492.2001. - DOI - PMC - PubMed
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