Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jun 9:11:370.
doi: 10.3389/fendo.2020.00370. eCollection 2020.

Vascular Complication in Adolescents With Diabetes Mellitus

Lara E Graves  1 , Kim C Donaghue  1   2
Affiliations
Review

Vascular Complication in Adolescents With Diabetes Mellitus

Lara E Graves et al. Front Endocrinol (Lausanne). .

Abstract

Diabetes mellitus is becoming more prevalent and even with new advancements which improve glycaemic control, complications of diabetes are common. Vascular complications of diabetes include the microvascular complications: retinopathy, nephropathy, and peripheral and autonomic neuropathy. Macrovascular complications are also common in patients with diabetes and arguably more concerning as they confer a high mortality risk yet are sometimes under-treated. Risk factors for diabetes complications start to occur in childhood and adolescents and some youths may be diagnosed with complications before transition to adult care. This article discusses the prevalence, risk factors, screening, and treatment recommendations for vascular complications in children and adolescents with diabetes.

Keywords: diabetes complications; macrovascular; microvascular; nephropathy; neuropathy; retinopathy.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Retinal photography demonstrating proliferative retinopathy in a 15-year-old girl with 12 years diabetes duration and poor metabolic control. This had rapidly progressed from minimal retinopathy documented 2 years before.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Dabelea D. Diabetes in youth-looking backwards to inform the future: Kelly West Award Lecture 2017. Diabetes Care. (2018) 41:233–40. 10.2337/dci17-0031 - DOI - PMC - PubMed
    1. Hamman RF, Bell RA, Dabelea D, D'Agostino RB, Jr, Dolan L, et al. . The SEARCH for diabetes in youth study: Rationale, findings, and future directions. Diabetes Care. (2014) 37:3336–44.d 10.2337/dc14-0574 - DOI - PMC - PubMed
    1. Dabelea D, Stafford JM, Mayer-Davis EJ, D'Agostino R, Jr, Dolan L, et al. . Association of type 1 diabetes vs. type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood. JAMA. (2017) 317:825–35. 10.1001/jama.2017.0686 - DOI - PMC - PubMed
    1. O'Connell PJ, Hawthorne WJ, Holmes-Walker DJ, Nankivell BJ, Gunton JE, Patel AT, et al. . Clinical islet transplantation in type 1 diabetes mellitus: Results of Australia's first trial. Med J Aust. (2006) 184:221–5. 10.5694/j.1326-5377.2006.tb00206.x - DOI - PubMed
    1. Katsarou A, Gudbjornsdottir S, Rawshani A, Dabelea D, Bonifacio E, Anderson BJ, et al. . Type 1 diabetes mellitus. Nat Rev Dis Primers. (2017) 3:17016. 10.1038/nrdp.2017.16 - DOI - PubMed