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Review
. 2020 Jun;54(3):128-138.
doi: 10.1007/s13139-020-00642-x. Epub 2020 May 9.

Radiogenomics Based on PET Imaging

Yong-Jin Park  1 , Mu Heon Shin  1 , Seung Hwan Moon  1
Affiliations
Review

Radiogenomics Based on PET Imaging

Yong-Jin Park et al. Nucl Med Mol Imaging. 2020 Jun.

Abstract

Radiogenomics or imaging genomics is a novel omics strategy of associating imaging data with genetic information, which has the potential to advance personalized medicine. Imaging features extracted from PET or PET/CT enable assessment of in vivo functional and physiological activity and provide comprehensive tumor information non-invasively. However, PET features are considered secondary to features on conventional imaging, and there has not yet been a review of the radiogenomic approach using PET features. This review article summarizes the current state of PET-based radiogenomic research for cancer, which discusses some of its limitations and directions for future study.

Keywords: Oncology; Positron emission tomography (PET); Radiogenomics.

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Conflict of interest statement

Conflict of InterestYong-Jin Park, Mu Heon Shin, and Seung Hwan Moon declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Details of the search strategy and process
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References

    1. Schillaci O, Urbano N. Personalized medicine: a new option for nuclear medicine and molecular imaging in the third millennium. Eur J Nucl Med Mol Imaging. 2017;44:563–566. - PubMed
    1. Bai HX, Lee AM, Yang L, Zhang P, Davatzikos C, Maris JM, et al. Imaging genomics in cancer research: limitations and promises. Br J Radiol. 2016;89:20151030. - PMC - PubMed
    1. Jaffe CC. Imaging and genomics: is there a synergy? Radiology. 2012;264:329–331. - PubMed
    1. Mazurowski MA. Radiogenomics: what it is and why it is important. J Am Coll Radiol. 2015;12:862–866. - PubMed
    1. Jansen RW, van Amstel P, Martens RM, Kooi IE, Wesseling P, de Langen AJ, et al. Non-invasive tumor genotyping using radiogenomic biomarkers, a systematic review and oncology-wide pathway analysis. Oncotarget. 2018;9:20134–20155. - PMC - PubMed

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