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. 2020 Dec 1;105(12):e4194-e4207.
doi: 10.1210/clinem/dgaa390.

Nonsurgical Management of Oligozoospermia

Jeremy T Choy  1   2 , John K Amory  3
Affiliations

Nonsurgical Management of Oligozoospermia

Jeremy T Choy et al. J Clin Endocrinol Metab. .

Abstract

Male infertility secondary to oligozoospermia is surprisingly common. Although a majority of cases are idiopathic, oligozoospermia can be caused by endocrine dysfunction, anatomic abnormalities, medications, or environmental exposures. The work-up includes excluding reversible factors such as hormonal deficiency, medication effects, and retrograde ejaculation and identifying any underlying genetic syndrome and treating reversible medical causes. If no reversible cause is found, appropriate referrals to urology and assisted reproductive technology should be initiated. Lastly, clinicians should be aware of and respond to the psychological and general health ramifications of a diagnosis of oligozoospermia as part of the comprehensive care of men and couples struggling with a diagnosis of infertility.

Keywords: FSH; LH; gonadotropins; male infertility; semen.

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Figures

Figure 1.
Figure 1.
The etiology of male infertility in 1737 consecutive men presenting to an infertility clinic. Data from Punab M, Poolamets O, Paju P, et al. Causes of male infertility in 1737 patients. Hum Reprod. 2017;32(1):18-31.
Figure 2.
Figure 2.
An approach to the evaluation and treatment of man with infertility from oligozoospermia. Abbreviations: ART, assisted reproductive technology; FSH, follicle-stimulating hormone; ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization; LH, luteinizing hormone.
See this image and copyright information in PMC

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