How promising is phototherapy for cancer?
- PMID: 32587359
- PMCID: PMC7492227
- DOI: 10.1038/s41416-020-0926-3
How promising is phototherapy for cancer?
Abstract
Oncological phototherapy, including current photodynamic therapy (PDT), developmental photoactivated chemotherapy (PACT) and photothermal therapy (PTT), shows promising photo-efficacy for superficial and internal tumours. The dual application of light and photochemotherapeutic agents allows accurate cancer targeting, low invasiveness and novel mechanisms of action. Current advances in new light sources and photoactive agents are encouraging for future development.
Conflict of interest statement
The authors declare no competing interests.
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References
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- Monro S, Colón KL, Yin H, Roque J, Konda P, Gujar S, Thummel RP, Lilge L, Cameron CG, McFarland SA. Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433. Chem. Rev. 2019;119:797–828. doi: 10.1021/acs.chemrev.8b00211. - DOI - PMC - PubMed
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