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. 2020 Jun 26;16(6):e1008940.
doi: 10.1371/journal.pgen.1008940. eCollection 2020 Jun.

Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

Cassandra R Diegel  1 , Steven Hann  2 , Ugur M Ayturk  2   3 , Jennifer C W Hu  2 , Kyung-Eun Lim  4 , Casey J Droscha  1 , Zachary B Madaj  5 , Gabrielle E Foxa  1 , Isaac Izaguirre  1 ; VAI Vivarium and Transgenics Core; Alexander G Robling  4 , Matthew L Warman  2 , Bart O Williams  1
Affiliations

Independent validation of experimental results requires timely and unrestricted access to animal models and reagents

Cassandra R Diegel et al. PLoS Genet. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. Diegel CR, Hann S, Ayturk UM, Hu JCW, Lim KE, et al. (2020) An osteocalcin-deficient mouse strain without endocrine abnormalities. PLoS Genet 16: e1008361 10.1371/journal.pgen.1008361 - DOI - PMC - PubMed
    1. Ducy P, Desbois C, Boyce B, Pinero G, Story B, et al. (1996) Increased bone formation in osteocalcin-deficient mice. Nature 382: 448–452. 10.1038/382448a0 - DOI - PubMed
    1. Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, et al. (2007) Endocrine regulation of energy metabolism by the skeleton. Cell 130: 456–469. 10.1016/j.cell.2007.05.047 - DOI - PMC - PubMed
    1. Oury F, Sumara G, Sumara O, Ferron M, Chang H, et al. (2011) Endocrine regulation of male fertility by the skeleton. Cell 144: 796–809. 10.1016/j.cell.2011.02.004 - DOI - PMC - PubMed
    1. Moriishi T, Ozasa R, Ishimoto T, Nakano T, Hasegawa T, et al. (2020) Osteocalcin is necessary for the alignment of apatite crystallites, but not glucose metabolism, testosterone synthesis, or muscle mass. PLoS Genet 16: e1008586 10.1371/journal.pgen.1008586 - DOI - PMC - PubMed