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Case Reports
. 2020 Sep 15:416:117001.
doi: 10.1016/j.jns.2020.117001. Epub 2020 Jun 18.

The association of SARS-CoV-2 infection and acute disseminated encephalomyelitis without prominent clinical pulmonary symptoms

Siamak Abdi  1 , Askar Ghorbani  2 , Farzad Fatehi  3
Affiliations
Case Reports

The association of SARS-CoV-2 infection and acute disseminated encephalomyelitis without prominent clinical pulmonary symptoms

Siamak Abdi et al. J Neurol Sci. .

Abstract

  1. •

    We describe a patient with acute disseminated encephalitis and COVID-19.

  2. •

    CNS manifestations primarily occurred without evident pulmonary symptoms.

  3. •

    Brain MRI of the patient indicated diffuse confluent white matter hyperintensities.

  4. •

    The patient initially responded to steroids but lastly, died of status epilepticus.

  5. •

    The occurrence of acute disseminated encephalitis may have been immune-mediated.

Keywords: Acute disseminated encephalomyelitis; Immune-mediated; SARS-CoV-2.

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Figures

Fig. 1
Fig. 1
Brain MRI of the patient indicates diffuse confluent white matter hyperintensity on FLAIR-weighted MRI, particularly at the left-side (A-D) without prominent enhancement on T1-weighted brain MRI (C, F). Moreover, the involvement of cortical (black arrow) as well as deep gray matter (black arrowhead), and dorsal midbrain (white arrow) is evident. The chest computed tomography (CT) scan (G, H) indicates bilateral multifocal peripheral consolidations with air-bronchogram consistent with SARS-CoV-2 infection.
See this image and copyright information in PMC

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