Response to the Comment on "ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO-Metastatic Tumor Burden in the Future Liver Remnant for Decision-making of Staged Hepatectomy"

Affiliations

¹ Department of Hepato-Pancreato-Biliary Surgery, Oslo University Hospital, Norway.
² Department of Surgical Gastroenterology and Transplantation, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
³ Department of Clinical Science, Intervention and Technology, Division of Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
⁴ Department of Surgery, Skane University Hospital, Lund, Sweden.
⁵ Department of Surgery, Akademiska University Hospital, Uppsala, Sweden.
⁶ Department of Surgery and Clinical and Experimental Medicine, Linköping University, Sweden.
⁷ Department of Transplantation and Liver Surgery, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Comment

Kristina Hasselgren et al. Ann Surg. 2021.

. 2021 Dec 1;274(6):e750-e751.

doi: 10.1097/SLA.0000000000004014.

¹ Department of Hepato-Pancreato-Biliary Surgery, Oslo University Hospital, Norway.
² Department of Surgical Gastroenterology and Transplantation, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
³ Department of Clinical Science, Intervention and Technology, Division of Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
⁴ Department of Surgery, Skane University Hospital, Lund, Sweden.
⁵ Department of Surgery, Akademiska University Hospital, Uppsala, Sweden.
⁶ Department of Surgery and Clinical and Experimental Medicine, Linköping University, Sweden.
⁷ Department of Transplantation and Liver Surgery, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

No abstract available

Conflict of interest statement

The authors report no conflicts of interest.

ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM: Survival Analysis From the Randomized Controlled Trial LIGRO.
Hasselgren K, Røsok BI, Larsen PN, Sparrelid E, Lindell G, Schultz NA, Bjørnbeth BA, Isaksson B, Larsson AL, Rizell M, Björnsson B, Sandström P. Hasselgren K, et al. Ann Surg. 2021 Mar 1;273(3):442-448. doi: 10.1097/SLA.0000000000003701. Ann Surg. 2021. PMID: 32049675 Clinical Trial.
Comment on "ALPPS Improves Survival Compared With TSH in Patients Affected of CRLM Survival Analysis From the Randomized Controlled Trial LIGRO": Metastatic Tumor Burden in the Future Liver Remnant for Decision-making of Staged Hepatectomy.
Chan KM, Wang YC, Wu TH, Cheng CH, Lee CF, Wu TJ, Chou HS, Lee WC. Chan KM, et al. Ann Surg. 2021 Dec 1;274(6):e749-e750. doi: 10.1097/SLA.0000000000004017. Ann Surg. 2021. PMID: 32590542 No abstract available.

1. Hasselgren K, Rosok BI, Larsen PN, et al. ALPPS improves survival compared with TSH in patients affected of CRLM: survival analysis from the randomized controlled trial LIGRO. Ann Surg 2019; p. 10.1097/SLA.0000000000003701. - DOI
1. Imai K, Benitez CC, Allard MA, et al. Failure to achieve a 2-Stage hepatectomy for colorectal liver metastases: how to prevent it? Ann Surg 2015; 262:772–778. discussion 778-9.
1. Sandstrom P, Rosok BI, Sparrelid E, et al. ALPPS improves resectability compared with conventional two-stage hepatectomy in patients with advanced colorectal liver metastasis: results from a Scandinavian multicenter randomized controlled trial (LIGRO Trial). Ann Surg 2018; 267:833–840.
1. Hasselgren K, Standstrom P, Rosok BI, et al. Future liver remnant (FLR) increase in patients with colorectal liver metastases is highest the first week after portal vein occlusion: FLR increase in patients with CRLM is highest the first week after PVO. J Gastrointest Surg 2019; 23:556–562.
1. Kambakamba P, Lineckar M, Alvarez FA, et al. Short chemotherapy-free interval improves oncological outcome in patients undergoing two-stage hepatectomy for colorectal liver metastases. Ann Surg Oncol 2016; 23:3915–3923.