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. 2020 Jun 21;44(3):121-131.
doi: 10.3906/biy-2005-29. eCollection 2020.

Covid-19: current knowledge, disease potential, prevention and clinical advances

Aftab Alam  1 , Mohd Faizan Siddiqui  2 , Nikhat Imam  3 , Rafat Ali  1 , Md Mushtaque  4 , Romana Ishrat  1
Affiliations

Covid-19: current knowledge, disease potential, prevention and clinical advances

Aftab Alam et al. Turk J Biol. .

Abstract

The top priority of any nation is to lead the nation towards prosperity, progress, and economic growth, confronting several challenges and concerns arisen from global situations. The sudden outbreak of any disease defies the health care systems and economy of nations. COVID-19 is one of the viral diseases which broke out in Wuhan city of China in 2019. COVID-19 outbreak intermittently prevailed all over the world. It exposes the fragility of the established health care systems across the world in spite of comprising modern science and technology. Unfortunately, there is no chemotherapeutic agent in the regimen of antiviral drugs or no vaccine available to curb this infectious disease. As a consequence, this deadly infection has prevailed all over the world. The antiviral drugs used for viral diseases excluding COVID-19 infection are Ramdesvir, Favipiravir, and Ribavarin, and antimalarial agents (Chloroquine & Hydroxychloroquine) are being administered to the patients for redemption of this infection. Fortunately, these existing drugs have been found clinically active and are being used. In this review, we present the current scenario and status of epidemiology, diagnosis, treatment, vaccine development for COVID-19, and its impact on the socio-economic structure.

Keywords: COVID-19; antivirals; financial crisis; mortality rate; transmission rate (Ro); vaccines.

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Conflict of interest statement

CONFLICT OF INTEREST: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Average basic reproduction number (R0) of most common viruses.
Figure 2
Figure 2
The chemotherapeutic agents exploited to curb the disease produced by COVID-19.
See this image and copyright information in PMC

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