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. 2020 Apr-Jun;14(2):178-185.
doi: 10.1590/1980-57642020dn14-020012.

Executive Functions in Parkinson's disease with and without Deep Brain Stimulation (DBS): A systematic review

Thayná Laís de Souza Arten  1 , Amer Cavalheiro Hamdan  2
Affiliations

Executive Functions in Parkinson's disease with and without Deep Brain Stimulation (DBS): A systematic review

Thayná Laís de Souza Arten et al. Dement Neuropsychol. 2020 Apr-Jun.

Abstract
in English, Portuguese

Given the aging of the world population, it is essential to investigate which methods are most effective for treating the diseases that manifest with age. This study addresses Parkinson's disease (PD), for which Deep Brain Stimulation (DBS) has been increasingly used to treat the disease.

Objective: To investigate Executive Functions (EF) in patients with and without DBS.

Methods: A systematic review of the literature was conducted according to the Preferred Reporting Items for Systematic Review and Meta-Analyzes (PRISMA) criteria. Scientific papers published on the Scopus, Web of Science and PsycInfo databases were selected.

Results: 13 articles were selected. Results showed no standardization of instruments used to evaluate EF and that, in most studies, lack of a control group may have affected results.

Conclusion: Decline in EF was observed in terms of verbal fluency and processing speed in patients with DBS.

Observando o envelhecimento da população mundial, é essencial investigar quais métodos são mais eficazes no tratamento das doenças que aparecem com a idade. Este estudo aborda a doença de Parkinson (DP). Na DP tem aumentado o uso da Estimulação Cerebral Profunda (DBS) para o tratamento da doença.

Objetivo: Investigar a Função Executiva (FE) em pacientes com e sem DBS.

Métodos: Foi realizada uma revisão sistemática da literatura de acordo com os critérios de Principais Itens para relatar Revisão Sistemática e Meta-Análises (PRISMA). Selecionamos artigos científicos publicados nas bases de dados Scopus, Web of Science e PsycInfo.

Resultados: 13 artigos foram selecionados. Observou-se que não há padronização nos instrumentos utilizados para avaliar a FE e, na maioria dos estudos, a falta de controle de grupo pode ter afetado os resultados.

Conclusão: Observou-se declínio na FE na fluência verbal e velocidade de processamento em pacientes com DBS.

Keywords: Deep Brain Stimulation; Executive Functions; Neuropsychological Assessment; Parkinson’s Disease.

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Conflict of interest statement

Disclosure: The authors report no conflicts of interest.

Figures

Figure 1
Figure 1. Literature search flow diagram.
See this image and copyright information in PMC

References

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