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. 2020 Jun;15(2):236-238.
doi: 10.1016/j.jds.2019.08.007. Epub 2019 Oct 15.

Primary intraosseous carcinoma of the mandible

Chia-Fu Yang  1 , Chih-Huang Tseng  2 , Yuk-Kwan Chen  2   3 , Chun-Ming Chen  1   4
Affiliations

Primary intraosseous carcinoma of the mandible

Chia-Fu Yang et al. J Dent Sci. 2020 Jun.
No abstract available

Keywords: Mandible; Primary intraosseous carcinoma; Survival rate.

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Conflict of interest statement

We have no conflicts of interest.

Figures

Figure 1
Figure 1
Radiographic photograph as well as histological and immunostained microphotographs of our case of intraosseous carcinoma. (A) Cropped panoramic radiograph showing a poorly-defined and non-corticated radiolucent lesion from the distal side of the right mandibular second premolar to the ascending ramus. (B) The tumor cells were arranged in trabeculae and islands infiltrating in the fibrous stroma with multifocal areas of tumoral necrosis (hematoxylin and eosin stain, original magnification 4×). (C) The tumor cells revealed nuclear hyperchromatism and pleomorphism, abnormal mitotic figures, and an increased nuclear to cytoplasmic ratio (hematoxylin and eosin stain, original magnification 20×). Immunohistochemical stains showed that the tumor cells were positive for CK (AE1/AE3) (D), CK7 (E), CK19 (F), and p40 (G); focally positive for CK20 (H); and negative for CD56 (I) and TTF-1 (J) (D to J, immunohistochemical stain; D to J, original magnification 4×).
See this image and copyright information in PMC

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