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Case Reports
. 2020 Oct;45(5):1187-1189.
doi: 10.1111/jcpt.13150. Epub 2020 Jun 29.

The first case of tegoprazan-induced urticaria

Da Woon Sim  1 , Ji Eun Yu  1 , Sun-Young Park  1 , Young-Il Koh  1
Affiliations
Case Reports

The first case of tegoprazan-induced urticaria

Da Woon Sim et al. J Clin Pharm Ther. 2020 Oct.

Abstract

What is known and objective: Tegoprazan induces adverse drug reactions during clinical trials; however, tegoprazan-induced urticaria has not been reported. Here, we describe the first case of this.

Case description: A 55-year-old woman presented with acute urticaria with pruritus after taking the gastro-oesophageal reflux disease medication, tegoprazan. Urticaria disappeared after tegoprazan discontinuation. In an oral provocation test, after taking 10% of tegoprazan, she developed pruritus, and after taking 30%, she developed urticaria on her back.

What is new and conclusion: This is the first case of urticaria induced by tegoprazan. Physicians should understand the possibility of a tegoprazan-induced hypersensitivity reactions.

Keywords: oral provocation test; tegoprazan; urticaria.

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References

REFERENCES

    1. Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 1943;2006(101):1900-1920.
    1. El-Serag HB, Sweet S, Winchester CC, Dent J. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2014;63:871-880.
    1. Kim KM, Cho YK, Bae SJ, et al. Prevalence of gastroesophageal reflux disease in Korea and associated health-care utilization: a national population-based study. J Gastroenterol Hepatol. 2012;27:741-745.
    1. Gyawali CP. Proton pump inhibitors in gastroesophageal reflux disease: friend or foe. Curr Gastroenterol Rep. 2017;19:46.
    1. Fass R, Ofman JJ, Sampliner RE, Camargo L, Wendel C, Fennerty MB. The omeprazole test is as sensitive as 24-h oesophageal pH monitoring in diagnosing gastro-oesophageal reflux disease in symptomatic patients with erosive oesophagitis. Aliment Pharmacol Ther. 2000;14:389-396.

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