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Review
. 2020 Jul;29(7):973-987.
doi: 10.1016/j.hlc.2020.05.101. Epub 2020 Jun 5.

SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart

Bishnu P Dhakal  1 , Nancy K Sweitzer  1 , Julia H Indik  1 , Deepak Acharya  1 , Preethi William  2
Affiliations
Review

SARS-CoV-2 Infection and Cardiovascular Disease: COVID-19 Heart

Bishnu P Dhakal et al. Heart Lung Circ. 2020 Jul.

Abstract

Coronavirus disease (COVID-19) is a serious illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The symptoms of the disease range from asymptomatic to mild respiratory symptoms and even potentially life-threatening cardiovascular and pulmonary complications. Cardiac complications include acute myocardial injury, arrhythmias, cardiogenic shock and even sudden death. Furthermore, drug interactions with COVID-19 therapies may place the patient at risk for arrhythmias, cardiomyopathy and sudden death. In this review, we summarise the cardiac manifestations of COVID-19 infection and propose a simplified algorithm for patient management during the COVID-19 pandemic.

Keywords: COVID; CV disease; Coronavirus; Myocarditis.

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Figures

Figure 1
Figure 1
Pathophysiology of COVID-19 infection.
Figure 2
Figure 2
COVID-19 treatment algorithm. Abbreviations: CBC, complete blood count; CMP, complete metabolic profile; ESR, erythrocyte sedimentation rate; CRP, C reactive protein; LDH, lactate dehydrogenase; CT, computed tomography; EKG (also ECG), electrocardiograph; BNP, NTpBNP, N terminal pro brain natriuretic peptide; Echo, echocardiograph; VT, ventricular tachycardia; PCI, percutaneous coronary intervention; STEMI, ST-elevation myocardial infarction; NSTEMI, non ST-elevation myocardial infarction; CTA; computed tomography angiography; ACS, acute coronary syndrome.
Figure 3
Figure 3
Prolonged QTc management algorithm.
See this image and copyright information in PMC

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