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. 2020 Jun;9(2):CNS55.
doi: 10.2217/cns-2020-0001. Epub 2020 Jun 30.

Epidemiologic and histologic characteristics of CNS lesions: a 20-year experience of a tertiary center in Lebanon

Roland Eid  1 , Stephanie Hage  1 , Ingrid Antonios  1 , Rita Moussa  1 , Makram Khoury  1 , Fady Ghassan Haddad  1 , Hampig Raphael Kourie  1 , Carole Kesrouani  2 , Claude Ghorra  2 , Gerard Abadjian  2 , Joseph Kattan  1
Affiliations

Epidemiologic and histologic characteristics of CNS lesions: a 20-year experience of a tertiary center in Lebanon

Roland Eid et al. CNS Oncol. 2020 Jun.

Abstract

Aim: Report the epidemiologic and histologic characteristics of CNS lesions in the Lebanese population. Methods: We conducted a retrospective study evaluating 2025 CNS lesions diagnosed between 1998 and 2017 in the pathology laboratory of a Lebanese tertiary center. Results: 52.2% of patients were men with a median age of 50 years. The most frequent symptoms were epilepsy (22.5%), headache (20.6%) and motor impairment (19.9%). 90.7% of tumors were primary. Lung (35.6%) and breast (16.5%) were the most frequent primaries of metastases. 46.2% of primary CNS tumors were glial, predominantly astrocytic (56.4%), and (42.5%) were nonglial, predominantly meningeal tumors (58%). Conclusion: Compared with Western literature, the Lebanese population is characterized by a younger age of onset of brain tumors, a lower rate of meningiomas and a higher rate of gliomas.

Keywords: CNS; Lebanese population; brain tumors; epidemiology.

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Conflict of interest statement

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

Figures

Figure 1.
Figure 1.. Collection and selection of records obtained from the pathology laboratory of Hôtel Dieu de France University hospital of Beirut from January 1998 to June 2017.
Figure 2.
Figure 2.. Distribution of histologic subtypes of all brain tumoral lesions collected from the pathology laboratory of Hôtel Dieu de France University hospital of Beirut from January 1998 to June 2017.
*Median age is represented in years between square brackets.
Figure 3.
Figure 3.. Distribution by (A) histological subtypes and (B) sex of meningiomas diagnosed at Hôtel Dieu de France University hospital of Beirut from January 1998 to June 2017.
*Median age is represented in years between square brackets.
See this image and copyright information in PMC

References

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