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Case Reports
. 2020 Sep;40(3):398-402.
doi: 10.1097/WNO.0000000000001049.

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis and Myelitis in COVID-19

Siwei Zhou  1 , Edward C Jones-Lopez, Deepak J Soneji, Christina J Azevedo, Vivek R Patel
Affiliations
Case Reports

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis and Myelitis in COVID-19

Siwei Zhou et al. J Neuroophthalmol. 2020 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

V. R. Patel reports a compensated consulting relationship with Horizon Therapeutics, unrelated to the submitted work. C. J. Azevedo reports personal fees from Guerbet, LLC, Genentech, Biogen Idec, Novartis, Sanofi Genzyme, EMD Serono, and Alexion Pharmaceuticals, unrelated to the submitted work. The remaining authors report no conflicts of interest.

Figures

FIG. 1.
FIG. 1.
Color fundus photographs revealing bilateral disc edema and venous congestion, with retinal perivenous hemorrhages of the right eye, indicating severe axoplasmic and venous stasis at the level of the congested right optic nerve head.
FIG. 2.
FIG. 2.
Postcontrast T1-weighted axial fat-suppressed MRI of orbits reveals thickening and avid uniform enhancement of both optic nerves, extending contiguously from each globe through to the intracranial prechiasmal segments, without overt involvement of the chiasm itself.
FIG. 3.
FIG. 3.
A. Sagittal STIR MRI of the cervical spine demonstrating 3 contiguous segments of central cord hyperintensity and mild intrinsic thickening (bracketed area). B. Postcontrast T1-weighted sagittal image demonstrating patchy faint gadolinium enhancement of the same area (arrow), consistent with active inflammation. STIR, short inversion-time inversion recovery.
See this image and copyright information in PMC

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