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Randomized Controlled Trial
. 2020 Nov;33(6):e13941.
doi: 10.1111/dth.13941. Epub 2020 Aug 7.

A randomized split-face, investigator-blinded study of a picosecond Alexandrite laser for post-inflammatory erythema and acne scars

Xiang Wen  1   2 , Yong Li  1 , Michael R Hamblin  2   3 , Xian Jiang  1
Affiliations
Randomized Controlled Trial

A randomized split-face, investigator-blinded study of a picosecond Alexandrite laser for post-inflammatory erythema and acne scars

Xiang Wen et al. Dermatol Ther. 2020 Nov.

Abstract

The 755 nm picosecond Alexandrite laser has been demonstrated to be effective and well tolerated in patients with acne scars. In this split-face, investigator-blinded study, 16 patients with post-inflammatory erythema (PIE) and acne scars were randomized to receive laser treatment on half the face, with the other half serving as a control. The treatment side demonstrated a significant improvement in both PIE and scars compared to the baseline and also when compared to the control side. Treatment was well-tolerated, with only transient and mild erythema and edema reported as side-effects. In our study, the picosecond Alexandrite laser was safe and effective in the treatment of PIE and acne scars. Comprehensive treatment outcomes should be taken into consideration when deciding on which device to use.

Keywords: acne scars; picosecond alexandrite laser; post-inflammatory erythema; randomized; split-face.

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References

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