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. 2020 Aug;64(4):356-361.
doi: 10.20945/2359-3997000000263. Epub 2020 Jun 29.

Cost effectiveness of intraoperative pathology in the management of indeterminate thyroid nodules

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Cost effectiveness of intraoperative pathology in the management of indeterminate thyroid nodules

Christopher D Vuong et al. Arch Endocrinol Metab. 2020 Aug.

Abstract

Objective This study aims to determine the cost effectiveness of rapid frozen section (RFS) for indeterminate thyroid nodules. Materials and methods A retrospective chart review was conducted between January 2009 and June 2013 at a tertiary care institution. Main outcomes were number needed to treat, RFS efficacy, and cost-savings of avoiding second completion thyroidectomy. Cost-effectiveness was estimated using 2015 Medicare reimbursement rate. Results Out of 1,114 patients undergoing thyroid surgery, 314 had preoperative AUS/FLUS cytopathology and subsequent thyroid lobectomy with RFS. RFS identified 13 of the 32 patients with malignancy resulting in a total thyroidectomy. 19 of the 29 malignancies not detected by RFS were papillary microcarcinomas. Conclusions Completion thyroidectomy was avoided in 1 out of every 24 patients resulting in cost-savings of $ 80.04 per patient. In the era of outpatient thyroid surgery, intraoperative RFS for indeterminate thyroid nodules is cost-effective.

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Conflict of interest statement

Disclosure: no potential conflict of interest relevant to this article was reported.

Figures

Figure 1
Figure 1. Results of Bethesda class III surgery with intraoperative consultation at our institution.

Comment in

References

    1. McKee G. The role of fine needle aspiration cytology in the diagnosis of thyroid lesions. J R Soc Med. 1998;91(Suppl 33): 28-32. - PMC - PubMed
    1. Baloch ZW, Cibas ES, Clark DP, Layfield LJ, Ljung BM, Pitman MB, et al. The National Cancer Institute Thyroid fine needle aspiration state of the science conference: a summation. Cytojournal. 2008;5:6. - PMC - PubMed
    1. Kiernan CM, Broome JT, Solórzano CC. The Bethesda system for reporting thyroid cytopathology: a single-center experience over 5 years. Ann Surg Oncol. 2014;21(11):3522-7. - PMC - PubMed
    1. Roach JC, Heller KS, Dubner S, Sznyter LA. The value of frozen section examinations in determining the extent of thyroid surgery in patients with indeterminate fine-needle aspiration cytology. Arch Otolaryngol Head Neck Surg. 2002;128(3):263-7. - PubMed
    1. Yoon JH, Kwak JY, Kim EK, Moon HJ, Kim MJ, Kim JY, et al. How to approach thyroid nodules with indeterminate cytology. Ann Surg Oncol. 2010;17(8):2147-55. - PubMed

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