Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study

Nikesh Dattani^{1

2}, Joseph Shalhoub^{3

2}, Sandip Nandhra^{4

2}, Tristan Lane^{5

2}, Abdulsalam Abu-Own^{6

2}, Ahmed Elbasty^{7

2}, Aled Jones^{8

2}, Andrew Duncan^{9

2}, Andrew Garnham^{10

2}, Ankur Thapar^{11

2}, Anna Murray^{12

2}, Anzar Baig^{13

2}, Athanasios Saratzis^{9

2}, Atif Sharif^{14

2}, Bella Huasen^{15

2}, Claire Dawkins^{16

2}, Craig Nesbitt^{17

2}, Daniel Carradice^{18

2}, Darren Morrow^{13

2}, David Bosanquet^{19

2}, Eamon Kavanagh^{20

21

2}, Faisal Shaikh^{22

2}, Gergely Gosi^{23

2}, Graeme Ambler^{24

2}, Gregory Fulton^{25

2}, Gurdas Singh^{26

2}, Hannah Travers^{12

2}, Hayley Moore^{7

2}, James Olivier^{27

2}, Louise Hitchman^{18

2}, Martin O'Donohoe^{28

2}, Matthew Popplewell^{29

2}, Mekki Medani^{30

2}, Michael Jenkins^{3

2}, Mingzheng A Goh^{31

2}, Oliver Lyons^{31

2}, Olivia McBride^{32

2}, Paul Moxey^{33

2}, Philip Stather^{34

2}, Phillipa Burns^{32

2}, Rachel Forsythe^{35

2}, Rachel Sam^{12

2}, Ranjeet Brar^{36

2}, Robert Brightwell^{13

2}, Ruth Benson^{37

2}, Sarah Onida^{11

2}, Sharath Paravastu^{38

2}, Simon Lambracos^{39

2}, Srinivasa R Vallabhaneni^{40

2}, Stewart Walsh^{41

2}, Tasleem Aktar^{14

2}, Tony Moloney^{42

2}, Zola Mzimba^{43

2}, Isaac Nyamekye¹

Affiliations

¹ Worcestershire Acute Hospitals NHS Trust, The Vascular Surgery Unit, Worcester, Worcestershire, UK.
² *The Vascular and Endovascular Research Network (VERN) collaborators.
³ Imperial College Healthcare NHS Trust, London, UK.
⁴ Northern Vascular Centre, Freeman Hospital, Newcastle University, Newcastle Upon Tyne, UK.
⁵ Department of Surgery and Cancer, Imperial College London, Academic Section of Vascular Surgery, London, UK.
⁶ Colchester Hospital University NHS Foundation Trust, Colchester, Essex, UK.
⁷ Frimley Park Hospital NHS Foundation Trust, Frimley, Surrey, UK.
⁸ Royal Cornwall Hospitals NHS Trust, Truro, Cornwall, UK.
⁹ University Hospitals of Leicester NHS Trust, Leicester, UK.
¹⁰ Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
¹¹ Imperial College London, Academic Section of Vascular Surgery, London, UK.
¹² University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
¹³ Norfolk and Norwich University Hospital NHS Trust, Norwich, Norfolk, UK.
¹⁴ Dudley Group NHS Foundation Trust, Dudley, West Midlands, UK.
¹⁵ Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, UK.
¹⁶ Sunderland Royal Hospital, Sunderland, UK.
¹⁷ Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK.
¹⁸ Hull Royal Infirmary, Hull, Kingston upon Hull, UK.
¹⁹ Southmead Hospital, Bristol, UK.
²⁰ University of Limerick Hospitals Group, Vascular Surgery, Limerick, Ireland.
²¹ University of Limerick Graduate Entry Medical School, Limerick, Ireland.
²² Heartlands Hospital, Birmingham, West Midlands, UK.
²³ University Hospital Waterford, Vascular Surgery, Waterford, Ireland.
²⁴ Royal Gwent Hospital, Newport, UK.
²⁵ Cork University Hospital Group, Cork, Ireland.
²⁶ Guy's Hospital, London, UK.
²⁷ Musgrove Park Hospital, Taunton, Somerset, UK.
²⁸ Mater Misericordiae University Hospital, Dublin, Ireland.
²⁹ University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
³⁰ Beaumont Hospital, Dublin, Ireland.
³¹ Basildon University Hospital, Basildon, Essex, UK.
³² Edinburgh Royal Infirmary, Edinburgh, UK.
³³ St George's Hospital, Vascular Surgery, London, Tooting, UK.
³⁴ Addenbrooke's Hospital, Cambridge, Cambridgeshire, UK.
³⁵ Royal Infirmary of Edinburgh, Edinburgh, UK.
³⁶ Royal Free London NHS Foundation Trust, London, UK.
³⁷ University of Birmingham Institute of Cancer and Genomic Sciences, Birmingham, UK.
³⁸ Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, Gloucestershire, UK.
³⁹ Western Sussex Hospitals NHS Trust, Worthing, West Sussex, UK.
⁴⁰ Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
⁴¹ Lambe Institute for Translational Discipline of Surgery, National University of Ireland, Galway, Ireland.
⁴² University of Limerick Hospitals Group, Dooradoyle, Limerick, Ireland.
⁴³ Altnagelvin Hospitals Health and Social Services Trust, Londonderry, UK.

PMID: 32611228
DOI: 10.1177/0268355520936420

Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study

Nikesh Dattani et al. Phlebology. 2020 Oct.

. 2020 Oct;35(9):706-714.

doi: 10.1177/0268355520936420. Epub 2020 Jul 1.

Authors

Affiliations

¹ Worcestershire Acute Hospitals NHS Trust, The Vascular Surgery Unit, Worcester, Worcestershire, UK.
² *The Vascular and Endovascular Research Network (VERN) collaborators.
³ Imperial College Healthcare NHS Trust, London, UK.
⁴ Northern Vascular Centre, Freeman Hospital, Newcastle University, Newcastle Upon Tyne, UK.
⁵ Department of Surgery and Cancer, Imperial College London, Academic Section of Vascular Surgery, London, UK.
⁶ Colchester Hospital University NHS Foundation Trust, Colchester, Essex, UK.
⁷ Frimley Park Hospital NHS Foundation Trust, Frimley, Surrey, UK.
⁸ Royal Cornwall Hospitals NHS Trust, Truro, Cornwall, UK.
⁹ University Hospitals of Leicester NHS Trust, Leicester, UK.
¹⁰ Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
¹¹ Imperial College London, Academic Section of Vascular Surgery, London, UK.
¹² University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
¹³ Norfolk and Norwich University Hospital NHS Trust, Norwich, Norfolk, UK.
¹⁴ Dudley Group NHS Foundation Trust, Dudley, West Midlands, UK.
¹⁵ Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, UK.
¹⁶ Sunderland Royal Hospital, Sunderland, UK.
¹⁷ Newcastle Upon Tyne Hospitals NHS Trust, Newcastle Upon Tyne, UK.
¹⁸ Hull Royal Infirmary, Hull, Kingston upon Hull, UK.
¹⁹ Southmead Hospital, Bristol, UK.
²⁰ University of Limerick Hospitals Group, Vascular Surgery, Limerick, Ireland.
²¹ University of Limerick Graduate Entry Medical School, Limerick, Ireland.
²² Heartlands Hospital, Birmingham, West Midlands, UK.
²³ University Hospital Waterford, Vascular Surgery, Waterford, Ireland.
²⁴ Royal Gwent Hospital, Newport, UK.
²⁵ Cork University Hospital Group, Cork, Ireland.
²⁶ Guy's Hospital, London, UK.
²⁷ Musgrove Park Hospital, Taunton, Somerset, UK.
²⁸ Mater Misericordiae University Hospital, Dublin, Ireland.
²⁹ University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
³⁰ Beaumont Hospital, Dublin, Ireland.
³¹ Basildon University Hospital, Basildon, Essex, UK.
³² Edinburgh Royal Infirmary, Edinburgh, UK.
³³ St George's Hospital, Vascular Surgery, London, Tooting, UK.
³⁴ Addenbrooke's Hospital, Cambridge, Cambridgeshire, UK.
³⁵ Royal Infirmary of Edinburgh, Edinburgh, UK.
³⁶ Royal Free London NHS Foundation Trust, London, UK.
³⁷ University of Birmingham Institute of Cancer and Genomic Sciences, Birmingham, UK.
³⁸ Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, Gloucestershire, UK.
³⁹ Western Sussex Hospitals NHS Trust, Worthing, West Sussex, UK.
⁴⁰ Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
⁴¹ Lambe Institute for Translational Discipline of Surgery, National University of Ireland, Galway, Ireland.
⁴² University of Limerick Hospitals Group, Dooradoyle, Limerick, Ireland.
⁴³ Altnagelvin Hospitals Health and Social Services Trust, Londonderry, UK.

PMID: 32611228
DOI: 10.1177/0268355520936420

Erratum in

Corrigendum to Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study.
[No authors listed] [No authors listed] Phlebology. 2020 Dec;35(10):844. doi: 10.1177/0268355520944366. Epub 2020 Jul 27. Phlebology. 2020. PMID: 32720855 No abstract available.

Abstract

Objectives: Venous thromboembolism is a potentially fatal complication of superficial endovenous treatment. Proper risk assessment and thromboprophylaxis could mitigate this hazard; however, there are currently no evidence-based or consensus guidelines. This study surveyed UK and Republic of Ireland vascular consultants to determine areas of consensus.

Methods: A 32-item survey was sent to vascular consultants via the Vascular and Endovascular Research Network (phase 1). These results generated 10 consensus statements which were redistributed (phase 2). 'Good' and 'very good' consensus were defined as endorsement/rejection of statements by >67% and >85% of respondents, respectively.

Results: Forty-two consultants completed phase 1. This generated seven statements regarding risk factors mandating peri-procedural pharmacoprophylaxis and three statements regarding specific pharmacoprophylaxis regimes. Forty-seven consultants completed phase 2. Regarding venous thromboembolism risk factors mandating pharmacoprophylaxis, 'good' and 'very good' consensus was achieved for 5/7 and 2/7 statements, respectively. Regarding specific regimens, 'very good' consensus was achieved for 3/3 statements.

Conclusions: The main findings from this study were that there was 'good' or 'very good' consensus that patients with any of the seven surveyed risk factors should be given pharmacoprophylaxis with low-molecular-weight heparin. High-risk patients should receive one to two weeks of pharmacoprophylaxis rather than a single dose.

Keywords: Deep vein thrombosis; VTE management; varicose veins; venous thromboembolism.

PubMed Disclaimer

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions

Grants and funding

NIHR300059/DH_/Department of Health/United Kingdom

LinkOut - more resources

Full Text Sources
- Atypon
- Ovid Technologies, Inc.

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study

Affiliations

Reducing the risk of venous thromboembolism following superficial endovenous treatment: A UK and Republic of Ireland consensus study

Authors

Affiliations

Erratum in

Abstract

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources