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Editorial
. 2020 Aug 7;15(8):1075-1077.
doi: 10.2215/CJN.08890620. Epub 2020 Jul 1.

Adverse Drug Effects in Patients with CKD: Primum Non Nocere

Mark A Perazella  1   2 , Thomas D Nolin  3
Affiliations
Editorial

Adverse Drug Effects in Patients with CKD: Primum Non Nocere

Mark A Perazella et al. Clin J Am Soc Nephrol. .
No abstract available

Keywords: acute kidney injury; chronic; chronic kidney disease; drug toxicity; drug-related side effects and adverse reactions; glomerular filtration rate; hemorrhage; pharmacology; renal insufficiency; renin-angiotensin system blockers.

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Figures

Figure 1.
Figure 1.
Factors that affect clinical pharmacology in humans. Reprinted from reference , with permission.
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Comment on

  • Adverse Drug Reactions in Patients with CKD.
    Laville SM, Gras-Champel V, Moragny J, Metzger M, Jacquelinet C, Combe C, Fouque D, Laville M, Frimat L, Robinson BM, Stengel B, Massy ZA, Liabeuf S; Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) Study Group. Laville SM, et al. Clin J Am Soc Nephrol. 2020 Aug 7;15(8):1090-1102. doi: 10.2215/CJN.01030120. Epub 2020 Jul 1. Clin J Am Soc Nephrol. 2020. PMID: 32611662 Free PMC article.

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    1. Nolin TD: A synopsis of clinical pharmacokinetic alterations in advanced CKD. Semin Dial 28: 325–329, 2015. - PMC - PubMed
    1. Roberts DM, Sevastos J, Carland JE, Stocker SL, Lea-Henry TN: Clinical pharmacokinetics in kidney disease: Application to rational design of dosing regimens. Clin J Am Soc Nephrol 13: 1254–1263, 2018. - PMC - PubMed
    1. Keller F, Hann A: Clinical pharmacodynamics: Principles of drug response and alterations in kidney disease. Clin J Am Soc Nephrol 13: 1413–1420, 2018. - PMC - PubMed

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